U-101958 Maleate (CAS 224170-09-6)
QUICK LINKS
U-101958 Maleate is a selective ligand for the D4 dopamine receptor (D4DR), exhibiting a dual function that varies across different experimental systems, where it can act either as an agonist or an antagonist. This unique flexibility makes it particularly valuable in neuroscientific research, where it is used to elucidate the specific roles and mechanisms of D4DRs in neural activity and behavior. By selectively interacting with this receptor subtype, U-101958 Maleate helps in dissecting the complex signaling pathways and functional dynamics of dopamine in the brain, contributing significantly to our understanding of dopaminergic modulation in neurological processes. Its ability to switch between agonistic and antagonistic actions provides a powerful tool for researchers to manipulate D4DR activity under controlled experimental conditions, thereby exploring the receptor′s involvement in cognitive functions and neuropsychiatric disorders.
U-101958 Maleate (CAS 224170-09-6) References
- Dopamine D(2) receptor activation causes mitogenesis via p44/42 mitogen-activated protein kinase in opossum kidney cells. | Narkar, VA., et al. 2001. J Am Soc Nephrol. 12: 1844-1852. PMID: 11518777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
U-101958 Maleate, 5 mg | sc-222396 | 5 mg | $305.00 |