Molecular structure of Tyrphostin B44, (+) enantiomer, CAS Number: 133550-37-5
Tyrphostin B44, (+) enantiomer (CAS 133550-37-5)
Alternate Names:
Tyrphostin B50; (+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
Application:
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor
CAS Number:
133550-37-5
Molecular Weight:
308.34
Molecular Formula:
C18H16N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tyrphostin B44, (+) enantiomer is the epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 µM). Slightly less active than the (−) enantiomer
Tyrphostin B44, (+) enantiomer (CAS 133550-37-5) References
- Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. | Gazit, A., et al. 1991. J Med Chem. 34: 1896-907. PMID: 1676428
Inhibitor of:
EGFR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tyrphostin B44, (+) enantiomer, 5 mg | sc-203305 | 5 mg | $30.00 |