Tyrphostin AG 698 (CAS 134036-52-5)
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Tyrphostin AG 698 is a compound that functions as a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It exerts its mechanism of action by competitively binding to the ATP-binding site of the EGFR, thereby preventing the receptor from phosphorylating its downstream substrates. This inhibition ultimately disrupts the signaling cascade involved in cell proliferation, survival, and differentiation. By targeting the EGFR, Tyrphostin AG 698 interferes with the activation of various intracellular pathways, such as the Ras/Raf/MEK/ERK and PI3K/Akt pathways, which are for regulating cellular processes. Tyrphostin AG 698′s ability to block EGFR tyrosine kinase activity makes it useful for investigating the role of EGFR signaling in various cellular processes. Its mechanism of action at the molecular level provides insights into the regulatory networks within cells, contributing to a deeper understanding of cellular signaling pathways.
Tyrphostin AG 698 (CAS 134036-52-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tyrphostin AG 698, 5 mg | sc-222391 | 5 mg | $30.00 |