Molecular structure of Tyrphostin AG 1112, CAS Number: 153150-84-6
Tyrphostin AG 1112 (CAS 153150-84-6)
Application:
Tyrphostin AG 1112 is a casein kinase II inhibitor
CAS Number:
153150-84-6
Molecular Weight:
274.28
Molecular Formula:
C15H10N6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Tyrphostin AG 1112 functions as a potent and selective inhibitor of receptor tyrosine kinases. It exerts its mechanism of action by competitively binding to the ATP-binding site of the receptor tyrosine kinases, thereby preventing the phosphorylation of tyrosine residues and subsequent downstream signaling pathways. This inhibition ultimately leads to the suppression of cell proliferation, migration, and survival. Tyrphostin AG 1112 may effectively block the activation of various intracellular signaling pathways, such as the Ras/MAPK and PI3K/Akt pathways, which are important for cell growth and survival.
Tyrphostin AG 1112 (CAS 153150-84-6) References
- Action of 3 tyrphostin derivatives on casein kinase II from rat liver. | Kang, TB., et al. 1997. Zhongguo Yao Li Xue Bao. 18: 56-8. PMID: 10072895
- Protein kinase inhibitors as a therapeutic modality. | Levitzki, A. 2003. Acc Chem Res. 36: 462-9. PMID: 12809533
- Itaconic acid hybrids as potential anticancer agents. | Perković, I., et al. 2022. Mol Divers. 26: 1-14. PMID: 33043404
Inhibitor of:
Casein Kinase, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tyrphostin AG 1112, 1 mg | sc-216032 | 1 mg | $65.00 | |||
Tyrphostin AG 1112, 5 mg | sc-216032A | 5 mg | $304.00 |