Date published: 2026-4-27

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Tylosin tartrate (CAS 1405-54-5)

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Alternate Names:
Pharmasin
Application:
Tylosin tartrate is an antibiotic with a large macrocyclic lactone ring
CAS Number:
1405-54-5
Purity:
≥90%
Molecular Weight:
1066.19
Molecular Formula:
C46H77NO17•C4H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tylosin tartrate is an antibiotic with a large macrocyclic lactone ring and is originally produced from fermentation of Streptomyces fradiae. This compound may act to be effective in vitro against Staphylococcus intermedius and sensitive mycoplasma organisms. Although a lot of antibiotics tend to suppress the immune system, macrolide antibiotics have been reported to enhance the immune system when used in chicken models. Studies suggest that chronic exposure to this compound may have a negative effect on the respiratory system.


Tylosin tartrate (CAS 1405-54-5) References

  1. Tylosin depletion in edible tissues of turkeys.  |  Montesissa, C., et al. 1999. Food Addit Contam. 16: 405-10. PMID: 10755131
  2. Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts.  |  Litterio, NJ., et al. 2007. J Vet Med A Physiol Pathol Clin Med. 54: 30-5. PMID: 17359452
  3. Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro.  |  Scott, BA., et al. 2010. Vet Ther. 11: E1-7. PMID: 20960412
  4. Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens.  |  Ji, LW., et al. 2014. J Vet Pharmacol Ther. 37: 312-5. PMID: 24325541
  5. Occupational asthma due to tylosin tartrate.  |  Lee, HS., et al. 1989. Br J Ind Med. 46: 498-9. PMID: 2765423
  6. Macrolide-Resistance Selection in Tibetan Pigs with a High Load of Mycoplasma hyopneumoniae.  |  Qiu, G., et al. 2018. Microb Drug Resist. 24: 1043-1049. PMID: 29271698
  7. A review of the medical considerations of the use of tylosin and other macrolide antibiotics as additives in animal feeds.  |  Knothe, H. 1977. Infection. 5: 183-7. PMID: 334674
  8. When is it safe to eat different broiler chicken tissues after administration of doxycycline and tylosin mixture?  |  Monir, HH., et al. 2021. J Food Sci. 86: 1162-1171. PMID: 33598923
  9. Field-Realistic Tylosin Exposure Impacts Honey Bee Microbiota and Pathogen Susceptibility, Which Is Ameliorated by Native Gut Probiotics.  |  Powell, JE., et al. 2021. Microbiol Spectr. 9: e0010321. PMID: 34160267
  10. Pharmacopoeial procedure for the determination of tylosin factors by high-performance liquid chromatography.  |  Fish, BJ. and Carr, GP. 1986. J Chromatogr. 353: 39-50. PMID: 3700523
  11. A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas.  |  Stipkovits, L., et al. 1984. Vet Microbiol. 9: 147-53. PMID: 6730305
  12. Tylosin tartrate and tiamutilin effects on experimental piglet pneumonia induced with pneumonic pig lung homogenate containing mycoplasmas, bacteria and viruses.  |  Hannan, PC., et al. 1982. Res Vet Sci. 33: 76-88. PMID: 7134653
  13. Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels.  |  Ziv, G., et al. 1995. J Vet Pharmacol Ther. 18: 299-305. PMID: 8583543
  14. Effect of tylosin tartrate on humoral immune responses in chickens.  |  Baba, T., et al. 1998. Zentralbl Veterinarmed B. 45: 279-86. PMID: 9673579

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tylosin tartrate, 1 g

sc-204933
1 g
$43.00

Tylosin tartrate, 5 g

sc-204933A
5 g
$160.00

Tylosin tartrate, 10 g

sc-204933B
10 g
$306.00

Tylosin tartrate, 50 g

sc-204933C
50 g
$1428.00

Tylosin tartrate, 100 g

sc-204933D
100 g
$2820.00