Tubulin Antibody (5F131): sc-73242
- Tubulin Antibody (5F131) is a mouse monoclonal IgM, cited in 45 publications, provided at 500 µl supernatant
- raised against skeletal muscle cell preparation of chicken origin
- recommended for detection of Tubulin of avian origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Tubulin Antibody (5F131). This work is in progress.
QUICK LINKS
SEE ALSO...
Tubulin Antibody (5F131) is a mouse monoclonal IgM antibody that detects Tubulin of avian origin by western blotting (WB) and immunofluorescence (IF). Anti-Tubulin antibody (5F131) is available in non-conjugated form, providing researchers with a versatile tool for studying this essential protein. Tubulin is a major component of the cytoskeleton, playing a critical role in maintaining cell shape, enabling intracellular transport, and facilitating cell division. Tubulin exists in five distinct forms, namely α, β, γ, δ, and ε Tubulin, with α and β Tubulins forming heterodimers that polymerize to create microtubule filaments. The dynamic nature of microtubules is crucial for various cellular processes, including mitosis and the transport of organelles and vesicles. γ Tubulin is integral to the formation of the gammasome, which is essential for microtubule nucleation at the centrosome, thereby influencing the organization of the mitotic spindle. Multiple β Tubulin isoforms, such as β1, β2, β3, β4, β5, β6, and β8, highlight the complexity of tubulin′s role in different tissues, with specific isoforms being localized to distinct cellular compartments. β3 Tubulin is uniquely expressed in neurons, underscoring its importance in neuronal function and development. The diverse functions and interactions of Tubulin make anti-Tubulin antibody (5F131) an invaluable resource for researchers investigating cytoskeletal dynamics and cellular architecture in avian models.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Tubulin Antibody (5F131) References:
- Presence of the betaII isotype of tubulin in the nuclei of cultured mesangial cells from rat kidney. | Walss, C., et al. 1999. Cell Motil Cytoskeleton. 42: 274-84. PMID: 10223634
- Identification of betaIII- and betaIV-tubulin isotypes in cold-adapted microtubules from Atlantic cod (Gadus morhua): antibody mapping and cDNA sequencing. | Modig, C., et al. 1999. Cell Motil Cytoskeleton. 42: 315-30. PMID: 10223637
- Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. | Chang, P. and Stearns, T. 2000. Nat Cell Biol. 2: 30-5. PMID: 10620804
- Tubulin immunoreactive neuronal intranuclear inclusions in the human brain. | Woulfe, J. and Munoz, D. 2000. Neuropathol Appl Neurobiol. 26: 161-71. PMID: 10840279
- Alpha-, beta-, and gamma-tubulins: sequence comparisons and structural constraints. | Burns, RG. 1991. Cell Motil Cytoskeleton. 20: 181-9. PMID: 1773446
- Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome. | Zheng, Y., et al. 1991. Cell. 65: 817-23. PMID: 1904010
- Invited review: the role of nucleotide triphosphate in actin and tubulin assembly and function. | Weisenberg, RC. 1981. Cell Motil. 1: 485-97. PMID: 6756643
- Multiple forms of tubulin: different gene products and covalent modifications. | Ludueña, RF. 1998. Int Rev Cytol. 178: 207-75. PMID: 9348671
- Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells. | Leask, A. and Stearns, T. 1998. J Biol Chem. 273: 2661-8. PMID: 9446570
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tubulin Antibody (5F131) | sc-73242 | 500 µl supernatant | $316.00 |