Molecular structure of (+)-Tubocurarine chloride pentahydrate, CAS Number: 6989-98-6
(+)-Tubocurarine chloride pentahydrate (CAS 6989-98-6)
Alternate Names:
Tubocurarine; d-Tubocurarine chloride pentahydrate
Application:
(+)-Tubocurarine chloride pentahydrate is an inhibitor of AChR
CAS Number:
6989-98-6
Purity:
≥97%
Molecular Weight:
771.72
Molecular Formula:
C37H42Cl2N2O6•5H2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-Tubocurarine chloride pentahydrate is an alkaloid salt studied for its action as a neuromuscular blocking agent. When examined in controlled settings, it acts by antagonizing nicotinic acetylcholine receptors at the neuromuscular junction, which inhibits neurotransmission. In research applications, (+)-tubocurarine is used to understand the mechanics of synaptic transmission and to study the function of acetylcholine receptors under various experimental conditions. It is also employed in physiological studies to isolate neural pathways and understand the effects of neurotransmitter inhibition on muscle response. Additionally, this compound plays a role in the examination of receptor desensitization.
(+)-Tubocurarine chloride pentahydrate (CAS 6989-98-6) References
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- Electrical synaptic transmission requires a postsynaptic scaffolding protein. | Lasseigne, AM., et al. 2021. Elife. 10: PMID: 33908867
- Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity. | Yang, L., et al. 2023. Nat Commun. 14: 900. PMID: 36797299
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Inhibitor of:
AChR, AChRα1, GlyR α1 (GLRA1), and Rapsyn.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Tubocurarine chloride pentahydrate, 250 mg | sc-216029 | 250 mg | $132.00 | |||
(+)-Tubocurarine chloride pentahydrate, 1 g | sc-216029A | 1 g | $398.00 |