TSSC1 Antibody (C-7): sc-376124

TSSC1 Antibody (C-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects TSSC1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TSSC1 (C-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TSSC1, also known as tumor suppressing subtransferable candidate 1, is a 387 amino acid protein characterized by five WD repeat domains, which are crucial for mediating protein-protein interactions. TSSC1 is widely expressed in various tissues, highlighting its potential role in cellular processes. TSSC1 is believed to be involved in tumor suppression, as alterations in the gene encoding TSSC1 have been linked to several cancers, including lung, ovarian, and breast cancer, as well as other conditions such as rhabdomyosarcoma and Beckwith-Wiedemann syndrome. The presence of WD repeat domains in TSSC1 suggests interactions with specific proteins involved in cell cycle regulation and apoptosis, making TSSC1 a significant target for research in cancer biology and therapeutic development.

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TSSC1 Antibody (C-7) References:

1. Identification of four new translocations involving FGFR1 in myeloid disorders.  |  Sohal, J., et al. 2001. Genes Chromosomes Cancer. 32: 155-63. PMID: 11550283
2. Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes.  |  Chan, AS., et al. 2002. Oncogene. 21: 3029-37. PMID: 12082533
3. A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes.  |  Hu, RJ., et al. 1997. Genomics. 46: 9-17. PMID: 9403053
4. Subchromosomal assignment1 of the TSSC1 gene to human chromosome band 11p15.5 near the HBB gene cluster.  |  Scelfo, R., et al. 1998. Cytogenet Cell Genet. 83: 52-3. PMID: 9925925

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TSSC1 Antibody (C-7) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-TSSC1 Antibody (C-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TSSC1 Antibody (C-7) Specifications

Alternate Product Name: TSSC1

Product Clone Name: C-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-193

Epitope Target: TSSC1

Epitope Species: human

Product Reactivity/Detection: TSSC1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for TSSC1 Antibody (C-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin