Molecular structure of Trypsin Inhibitor, soybean, CAS Number: 9035-81-8
Trypsin Inhibitor, soybean (CAS 9035-81-8)
See product citations (14)
Alternate Names:
Trypsin Inhibitor, soybean is also known as SBTI.
Application:
Trypsin Inhibitor, soybean is a protein and inhibitor of trypsin factor Xa, plasmin and neutrophil elastase.
CAS Number:
9035-81-8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Trypsin Inhibitor, soybean (STI) is a protein which reduces trypsin (a proteolytic enzyme) as well as plasma kallikrein and plasmin activity. It has demonstrated inhibition of human neutrophil elastase at an IC50=0.3nM. At this concentration, Trypsin Inhibitor, soybean showed neither cytotoxic nor haemolytic effects on populations of human blood cells. In fibrin matrix, and without toxic effects, Trypsin Inhibitor, soybean had strong inhibitory effect on human umbilical vein, endothelial cells migration, and tubulogenesis. It has been observed that repeated administration of Trypsin Inhibitor, soybean to rats, especially suckling and young rats, causes the pancreas to enlarge. Trypsin Inhibitor, soybean is also known as SBTI, Trypsin Inhibitor, soybean, and Trypsin inhibitor from Glycine max.
Trypsin Inhibitor, soybean (CAS 9035-81-8) References
- Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin. | Zhu, J., et al. 2005. Am J Physiol Heart Circ Physiol. 288: H908-13. PMID: 15486030
- Anti-angiogenic effect of soybean kunitz trypsin inhibitor on human umbilical vein endothelial cells. | Shakiba, Y., et al. 2007. Fitoterapia. 78: 587-9. PMID: 17590534
- New properties of the soybean trypsin inhibitor: Inhibition of human neutrophil elastase and its effect on acute pulmonary injury. | Ribeiro, JK., et al. 2010. Eur J Pharmacol. 644: 238-44. PMID: 20624384
- Possible conformational change within the desolvated and cationized sBBI/trypsin non-covalent complex during the collision-induced dissociation process. | Darii, E., et al. 2011. Rapid Commun Mass Spectrom. 25: 1725-34. PMID: 21598332
- Profiling metabolite changes in the neuronal differentiation of human striatal neural stem cells using 1H-magnetic resonance spectroscopy. | Chung, YL., et al. 2013. Neuroreport. 24: 1035-40. PMID: 24145773
- Expression of CXCR1 (interleukin-8 receptor) in murine macrophages after staphylococcus aureus infection and its possible implication on intracellular survival correlating with cytokines and bacterial anti-oxidant enzymes. | Bishayi, B., et al. 2015. Inflammation. 38: 812-27. PMID: 25129059
- Phenylglyoxal-based visualization of citrullinated proteins on Western blots. | Hensen, SM., et al. 2015. Molecules. 20: 6592-600. PMID: 25875038
- Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. | Divakaruni, AS., et al. 2018. Cell Metab. 28: 490-503.e7. PMID: 30043752
- Evaluation of holographic imaging cytometer holomonitor M4® motility applications. | Zhang, Y. and Judson, RL. 2018. Cytometry A. 93: 1125-1131. PMID: 30343513
- CRISPR/Cas9 engineering of ERK5 identifies its FAK/PYK2 dependent role in adhesion-mediated cell survival. | Ali, M., et al. 2019. Biochem Biophys Res Commun. 513: 179-185. PMID: 30952431
- Targeted inactivation of soybean proteinase inhibitors using zinc. | Rehder, A., et al. 2021. Food Chem. 349: 129049. PMID: 33581435
- Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture. | Nichols, AEC., et al. 2021. FASEB J. 35: e21733. PMID: 34160846
- Efficient fabrication of stretching hydrogels with programmable strain gradients as cell sheet delivery vehicles. | Huang, R., et al. 2021. Mater Sci Eng C Mater Biol Appl. 129: 112415. PMID: 34579924
- Immunocytochemical study of the interaction of soybean trypsin inhibitor with rat intestinal mucosa. | Wilson, PA., et al. 1978. Gut. 19: 260-6. PMID: 348580
- Characterization of soybean trypsin inhibitor sensitive protease from unfertilized sea urchin eggs. | Alliegro, MC. and Schuel, H. 1985. Biochemistry. 24: 3926-31. PMID: 3902077
- Isolation and characterization of a wound-induced trypsin inhibitor from alfalfa leaves. | Brown, WE. and Ryan, CA. 1984. Biochemistry. 23: 3418-22. PMID: 6432043
Inhibitor of:
C1rL, Chymotrypsin, Corin, Enterokinase, Enzyme, granzyme C, Kininogen I, Klk1b4, Klk26, KLKb2, KLKBL4, Marapsin 2, Matriptase, MC-CPA, megsin, Neutrophil Elastase, Prss28, Prss29, Prss39, PRSS50, TESP3, TMPRSS11E, TMPRSS12, TMPRSS13, TMPRSS4, Trypsin, Trypsin X3, Trypsin-1, Trypsin-10, Trypsin-3, Trypsin-4, Trypsin-5, and TSP50.Activator of:
1700074P13Rik, Acrosin, CRISP-8, HAI-1, HSBP1L1, KLK15, Klk1b4, Klkb16, Klkb22, plasma kallikrein, PRSS16, Prss29, PRSS55, SerpinA1d, Tesp2, TESSP-1, TMPRSS11B, TMPRSS3, TMPRSSs8, TPSB1, Trypsin-10, and Trypsin-3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trypsin Inhibitor, soybean, 50 mg | sc-29129 | 50 mg | $36.00 | |||
Trypsin Inhibitor, soybean, 250 mg | sc-29129A | 250 mg | $129.00 | |||
Trypsin Inhibitor, soybean, 1 g | sc-29129B | 1 g | $262.00 | |||
Trypsin Inhibitor, soybean, 5 g | sc-29129C | 5 g | $940.00 | |||
Trypsin Inhibitor, soybean, 10 g | sc-29129D | 10 g | $1499.00 | |||
Trypsin Inhibitor, soybean, 25 g | sc-29129F | 25 g | $2580.00 | |||
Trypsin Inhibitor, soybean, 100 g | sc-29129E | 100 g | $10200.00 |