TRP1 Antibody (F-6): sc-166791
- TRP1 Antibody (F-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 448-537 of TRP1 of human origin
- recommended for detection of TRP1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See TRP1 (G-9): sc-166857 for TRP1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP is the preferred secondary detection reagent for TRP1 Antibody (F-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with TRP1 Antibody (F-6) (see ordering information below).
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TRP1 Antibody (F-6) is a mouse monoclonal IgG1 antibody that detects TRP1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TRP1, or tyrosinase-related protein 1, plays a crucial role in the biosynthesis of melanin, working alongside other proteins such as tyrosinase and TRP2 to facilitate pigment production. Located within the melanosomes of melanocytes, TRP1 is integral to the melanin synthesis pathway, contributing to the stability and activity of the multi-enzyme complex that includes tyrosinase. TRP1′s structure features a transmembrane domain and metal-binding sites, which are essential for enzymatic function. Additionally, TRP1 undergoes post-translational modifications that can influence activity and stability, making TRP1 a key player in pigmentation regulation. Deficiencies in TRP1 can lead to pigmentation disorders, highlighting TRP1′s importance in maintaining normal skin and hair color. Through interactions with other melanin biosynthesis proteins, TRP1 is vital for understanding mechanisms underlying pigmentation and related genetic conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRP1 Antibody (F-6) | sc-166791 | 200 µg/ml | $316.00 | |||
TRP1 Antibody (F-6): m-IgG1 BP-HRP Bundle | sc-542671 | 200 µg Ab; 20 µg BP | $354.00 |