TROY Antibody (4E8): sc-100312
- TROY Antibody (4E8) is a mouse monoclonal IgG1 κ provided at 50 µg/0.5 ml
- raised against recombinant TROY of human origin
- recommended for detection of TROY of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TROY Antibody (4E8). This work is in progress.
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SEE ALSO...
TROY Antibody (4E8) is a mouse monoclonal IgG1 antibody that detects TROY in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TROY, a member of the tumor necrosis factor receptor (TNFR) superfamily, plays a crucial role in cellular functions including proliferation, differentiation, and programmed cell death. TROY (4E8) monoclonal antibody enables research into cell survival and death through distinct signaling pathways. TROY exists in several isoforms, with the full-length version containing a cytoplasmic tail that interacts with tumor necrosis factor receptor-associated factor 2 (TRAF2), thereby promoting cell survival via the NFkB signaling pathway. TROY expression is notably found in the epithelium of various tissues, including the brain, heart, lung, and liver, highlighting its significance in developmental processes and tissue homeostasis. Additionally, a truncated isoform known as TNFRSF19 lacks the full cytoplasmic tail, which inhibits its ability to activate the NFkB pathway, thus providing a regulatory mechanism in cellular signaling. Anti-TROY antibody (4E8) serves as an essential tool for researchers investigating the complex roles of TROY in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TROY Antibody (4E8) | sc-100312 | 50 µg/0.5 ml | $339.00 |