Troponin T-C Antibody (A-11): sc-515899
- Troponin T-C Antibody (A-11) is a mouse monoclonal IgM κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 270-295 near the C-terminus of Troponin T-C of human origin
- recommended for detection of Troponin T-C of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin T-C Antibody (A-11). This work is in progress.
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Troponin T-C Antibody (A-11) is a mouse monoclonal IgM antibody that detects Troponin T in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Troponin T plays a critical role in muscle contraction by anchoring the troponin complex to actin filaments, facilitating interaction between actin and myosin during muscle contraction. Troponin T is predominantly located in cardiac and skeletal muscle tissues, where Troponin T is essential for regulating muscle contraction in response to calcium levels. Elevated Troponin T levels in the bloodstream serve as a key biomarker for myocardial infarction, making Troponin T an important target for clinical diagnostics. Troponin T′s structure includes a unique C-terminal domain that interacts with tropomyosin, stabilizing actin filaments and enabling proper muscle contraction. Anti-Troponin T antibody (A-11) proves valuable in both research and clinical applications due to Troponin T′s crucial role in muscle physiology and pathology through tropomyosin binding and troponin complex formation.
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Troponin T-C Antibody (A-11) References:
- Cardiac troponin T and C-reactive protein as markers of acute cardiac allograft rejection. | Chance, JJ., et al. 2001. Clin Chim Acta. 312: 31-9. PMID: 11580907
- High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis. | Dispenzieri, A., et al. 2014. Heart. 100: 383-8. PMID: 24402772
- Determinants of high sensitivity cardiac troponin T elevation in acute ischemic stroke. | Faiz, KW., et al. 2014. BMC Neurol. 14: 96. PMID: 24885286
- Clinical significance of high-sensitivity cardiac troponin T in patients with dilated cardiomyopathy. | Baba, Y., et al. 2015. Int Heart J. 56: 309-13. PMID: 25912901
- Elevated Plasma Cardiac Troponin T Levels Caused by Skeletal Muscle Damage in Pompe Disease. | Wens, SC., et al. 2016. Circ Cardiovasc Genet. 9: 6-13. PMID: 26787432
- Cardiac Troponin T and I Release After a 30-km Run. | Klinkenberg, LJ., et al. 2016. Am J Cardiol. 118: 281-7. PMID: 27282835
- Cardiac troponin T and fast skeletal muscle denervation in ageing. | Xu, Z., et al. 2017. J Cachexia Sarcopenia Muscle. 8: 808-823. PMID: 28419739
- High-Sensitivity Cardiac Troponin T Improves the Diagnosis of Perioperative MI. | Brown, JC., et al. 2017. Anesth Analg. 125: 1455-1462. PMID: 28719430
- High-Sensitivity Cardiac Troponin T levels in prehypertensive patients. | Askin, L. and Yesiltepe, Y. 2018. Clin Exp Hypertens. 40: 332-336. PMID: 28952796
- High-sensitivity cardiac troponin T increases after stress echocardiography. | Samaha, E., et al. 2019. Clin Biochem. 63: 18-23. PMID: 30502318
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin T-C Antibody (A-11) | sc-515899 | 200 µg/ml | $322.00 |