Troponin T-C Antibody (1.BB.155): sc-73234
- Troponin T-C Antibody (1.BB.155) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against full length cardiac troponin T of bovine origin
- recommended for detection of cardiac muscle Troponin T of human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and bovine, feline and canine
- See Troponin T-C (CT3): sc-20025 for Troponin T-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin T-C Antibody (1.BB.155). This work is in progress.
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Troponin T-C Antibody (1.BB.155) is a mouse monoclonal IgG1 antibody that detects Troponin T in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Troponin T plays a critical role in the regulation of muscle contraction by serving as a link between the troponin complex and the actin filaments in muscle cells. Anti-Troponin T antibody (1.BB.155) helps researchers study this protein′s essential role in proper functioning of cardiac and skeletal muscles, as Troponin T helps position the troponin complex on the thin filament, allowing for precise control of muscle contraction in response to calcium levels. The structure of Troponin T is particularly important because specific regions interact with both Troponin I and Troponin C, facilitating the conformational changes necessary for muscle contraction. Several Troponin T isoforms are expressed in different muscle types, which can influence the contractile properties and responsiveness of muscle tissue. The binding of Troponin T to actin and interaction with other troponin subunits are vital for muscle contraction regulation, making Troponin T monoclonal antibody (1.BB.155) an invaluable tool for investigating muscle function and related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
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Troponin T-C Antibody (1.BB.155) References:
- Cardiac troponin T in patients with kidney disease. | Hojs, R. 2005. Ther Apher Dial. 9: 205-7. PMID: 15966989
- Cardiac troponin T: from diagnosis of myocardial infarction to cardiovascular risk prediction. | Mueller, M., et al. 2013. Circ J. 77: 1653-61. PMID: 23803255
- Current applications of cardiac troponin T for the diagnosis of myocardial damage. | Vasatova, M., et al. 2013. Adv Clin Chem. 61: 33-65. PMID: 24015599
- Cardiac troponin T (TNNT2) mutations in chinese dilated cardiomyopathy patients. | Li, X., et al. 2014. Biomed Res Int. 2014: 907360. PMID: 25110706
- High-Sensitivity Cardiac Troponin T and Risk of Hypertension. | McEvoy, JW., et al. 2015. Circulation. 132: 825-33. PMID: 26152706
- Cardiac troponin T in patients with cardiac implantable electronic devices undergoing magnetic resonance imaging. | Higgins, JV., et al. 2016. J Interv Card Electrophysiol. 45: 91-7. PMID: 26489609
- Multiple Species Comparison of Cardiac Troponin T and Dystrophin: Unravelling the DNA behind Dilated Cardiomyopathy. | England, J., et al. 2017. J Cardiovasc Dev Dis. 4: PMID: 29367539
- Cardiac Troponin T: The Impact of Posttranslational Modifications on Analytical Immunoreactivity in Blood up to the Excretion in Urine. | de Boer, D., et al. 2021. Adv Exp Med Biol. 1306: 41-59. PMID: 33959905
- Cardiac troponin T and NT-proBNP for detecting myocardial ischemia in suspected chronic coronary syndrome. | Myhre, PL., et al. 2022. Int J Cardiol. 361: 14-17. PMID: 35577165
- Cardiac troponin T in extracellular vesicles as a novel biomarker in human cardiovascular disease. | Lennon, KM., et al. 2022. Clin Transl Med. 12: e979. PMID: 35988159
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin T-C Antibody (1.BB.155) | sc-73234 | 100 µg/ml | $322.00 |