Troponin I-C Antibody (TPC-14): sc-69851

Troponin I-C Antibody (TPC-14) is a mouse monoclonal IgG2a antibody engineered to detect recombinant full-length cardiac Troponin I-C (cTnI-C), also known as cardiac troponin I, a pivotal regulator of cardiac muscle contraction. Anti-cTnI-C antibody (TPC-14) targets an epitope within amino acids 1-31 of human cTnI-C, ensuring precise binding and consistent performance across various applications. Located within the sarcomere of cardiac muscle cells, cTnI-C plays a crucial role in regulating the interaction between actin and myosin in response to calcium ion concentrations, thereby controlling muscle contraction and relaxation. cTnI-C monoclonal antibody (TPC-14) facilitates the investigation of interactions with other key proteins such as Troponin T (cTnT) and Troponin C (cTnC), as well as actin and myosin, which are essential for maintaining cardiac function and integrity. Anti-cTnI-C antibody (TPC-14) exhibits robust reactivity with cTnI-C from mouse, rat, and human origins, making this clone versatile for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) techniques. Understanding the precise localization and interactions of cTnI-C is vital for elucidating the mechanisms underlying cardiac muscle physiology and various pathological conditions, including heart failure and myocardial infarction. cTnI-C (TPC-14) antibody is an indispensable tool for researchers studying cardiac biomarkers, muscle contraction dynamics, and related diseases.

The preferred Troponin I antibody is Troponin I Antibody (E-9): sc-365446.