Troponin I-C Antibody (M46): sc-52277

Troponin I-C Antibody (M46) is a mouse monoclonal IgG1 antibody designed to detect cardiac Troponin I (cTnI), a critical regulator of muscle contraction in cardiac tissue. Anti-Troponin I-C antibody (M46) targets an epitope mapped to amino acids 130-145 of human cTnI, ensuring precise binding and reliable detection in various applications. cTnI, also known as cardiac troponin I, is an essential component of the troponin complex, which includes Troponin T (cTnT) and Troponin C (cTnC), collectively regulating the interaction between actin and myosin in response to calcium levels. By binding to cTnI, Troponin I-C monoclonal antibody (M46) facilitates the study of its interactions with other proteins such as actin and myosin, as well as its role in muscle contraction and cardiac function. Troponin I-C mouse monoclonal antibody (M46) exhibits robust reactivity with free cTnI and cTnI when complexed with other troponin components across multiple species, including mouse, rat, and human, making it versatile for use in western blotting (WB) and immunoprecipitation (IP) techniques. The ability to detect both native and denatured forms of cTnI allows for comprehensive analysis of its expression and regulation in different experimental conditions. Additionally, cTnI interacts with regulatory proteins like tropomyosin, further highlighting its pivotal role in the cardiac muscle contractile apparatus. Troponin I-C (M46) antibody is an invaluable tool for researchers investigating cardiac biomarkers, muscle physiology, and related pathological conditions.

The preferred Troponin I antibody is Troponin I Antibody (E-9): sc-365446.