Troponin I-C Antibody (267): sc-52270

Troponin I-C Antibody (267) is a mouse monoclonal IgG2a antibody engineered to detect cardiac Troponin I (cTnI), also known as TNNI3, a critical component of the troponin complex in cardiac muscle cells. Anti-Troponin I-C antibody (267) targets the epitope mapped to amino acids 169-184 of synthetic human cardiac Troponin I, ensuring accurate and reliable binding. Troponin I plays a pivotal role in muscle contraction by inhibiting the interaction between actin and myosin in the absence of calcium, thereby regulating the contraction and relaxation cycles essential for heart function. Structurally, Troponin I consists of distinct domains that interact with actin and tropomyosin, facilitating precise control over muscle contraction at the molecular level. The structural integrity of Troponin I is vital for its function, as this ensures proper regulation of cardiac muscle contraction and responsiveness to physiological signals. Troponin I-C monoclonal antibody (267) is recommended for detecting cardiac muscle Troponin I from mouse, rat, and human origins, and is suitable for applications such as western blotting (WB) and immunoprecipitation (IP). By targeting a structurally essential protein within the cardiac sarcomere, Troponin I-C (267) antibody is an invaluable tool for research into cardiac physiology, disease mechanisms, and the development of diagnostic assays for cardiac injuries like myocardial infarction. Anti-Troponin I-C antibody (267) supports advanced investigations into heart health and disease, contributing to the development of effective therapeutic and diagnostic strategies.

The preferred Troponin I antibody is Troponin I Antibody (E-9): sc-365446.