Tropisetron hydrochloride is a potent SR (SR-3) antagonist. It is also a selective, partial agonist at AChR α 7 (α7 nicotinic receptors). Tropisetron hydrochloride is an inhibitor of HTR3.
Tonini M, Candura SM Onori L et al. Life Sci. 50:PL173-8 (1992). Seynaeve et al (1991) 5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron. Anticancer Drugs 2 343. Middlemiss and Tricklebank (1992) Ce
Soluble in water (100 mM), DMSO (50 mM), and methanol.
Store at 4° C
283-285° C (dec.)
448.5° C at 760 mmHg (Predicted)
n20D 1.64 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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