Anti-TROP-2 Antibody (B-9) is a mouse monoclonal IgG1 (kappa light chain) TROP-2 antibody provided at 200 µg/ml
raised against amino acids 141-225 mapping within an internal region of TROP-2 of human origin
TROP-2 Antibody (B-9) is recommended for detection of TROP-2 of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-TROP-2 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TROP-2 (B-9): sc-376746.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TROP-2 Antibody (B-9) is a high quality monoclonal TROP-2 antibody (also designated TROP-2 antibody) suitable for the detection of the TROP-2 protein of human origin. TROP-2 Antibody (B-9) is available as both the non-conjugated anti-TROP-2 antibody form, as well as multiple conjugated forms of anti-TROP-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. TROP-2, also known as tumor-associated calcium signal transducer 2 (TACSTD2), pancreatic carcinoma marker protein GA733-1, membrane component chromosome 1, surface marker 1 (M1S1) or epithelial glycoprotein-1 (EGP-1), is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thryoglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. TROP-2 plays a role in tranducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multistratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells. Mutations in the gene encoding TROP-2 can result in gelatinous drop-like corneal dystrophy (GDLD) also referred to as lattice corneal dystrophy type III, an autosomal recessive disorder that causes severe visual impairment.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Can TROP-2 (B-9): sc-376746 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?
Asked by: Dr Ninau Qelp
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, TROP-2 (B-9): sc-376746 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Rated 5 out of
Strong StainingExcellent strength of stain seen when used in IHC with FFPE human tissue samples.
Date published: 2017-01-23
Rated 5 out of
EC H from
Great Western Blot antibodyWe have Trop2 knock-out and overexpression stable cell lines. The Western blot staining show pretty good specificity and sensitivity. Single band and no non-specific binding.
Date published: 2016-10-26
Rated 5 out of
Produced exceptional immunoperoxidase membraneProduced exceptional immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human skin tissue. -SCBT QC
Date published: 2015-04-18
Rated 5 out of
Good Western Blot data of TROPGood Western Blot data of TROP-2 expression in non-transfected and human TROP-2 transfected 293T whole cell lysates. -SCBT QC
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