Date published: 2025-12-18

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Tris(4-isopropylphenyl) phosphate (CAS 68937-41-7)

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Alternate Names:
Tris[4-(propan-2-yl)phenyl] phosphate
CAS Number:
68937-41-7
Molecular Weight:
452.52
Molecular Formula:
C27H33O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tris(4-isopropylphenyl) phosphate (IPP) is an ester of isopropyl alcohol and phenyl phosphate, and can be used as a substrate for various enzymes, as a reagent for the synthesis of organic compounds, and as a catalyst in organic reactions. It is also used in the study of biochemical and physiological processes, such as the regulation of enzyme activity and the effects of environmental stress on cells. Furthermore, it has been employed to investigate the effects of aging and radiation on cells.


Tris(4-isopropylphenyl) phosphate (CAS 68937-41-7) References

  1. Prioritization of 10 organic flame retardants using an avian hepatocyte toxicogenomic assay.  |  Pagé-Larivière, F., et al. 2018. Environ Toxicol Chem. 37: 3134-3144. PMID: 30133003
  2. In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions.  |  Phillips, AL., et al. 2020. Chem Res Toxicol. 33: 1428-1441. PMID: 32129605
  3. Use of comprehensive target analysis for determination of contaminants of emerging concern in a sediment core collected from Beppu Bay, Japan.  |  Nishimuta, K., et al. 2021. Environ Pollut. 272: 115587. PMID: 33261969
  4. Organophosphorus-based chemical additives induced behavioral changes in zebrafish (Danio rerio): Swimming activity is a sensitive stress indicator.  |  Poopal, RK., et al. 2021. Neurotoxicol Teratol. 83: 106945. PMID: 33333156
  5. First study on the presence of plastic additives in loggerhead sea turtles (Caretta caretta) from the Mediterranean Sea.  |  Sala, B., et al. 2021. Environ Pollut. 283: 117108. PMID: 33866215
  6. Developmental and Hepatic Gene Expression Changes in Chicken Embryos Exposed to p-Tert-Butylphenyl Diphenyl Phosphate and Isopropylphenyl Phosphate via Egg Injection.  |  Nguyen, PTT., et al. 2022. Environ Toxicol Chem. 41: 739-747. PMID: 34913512

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tris(4-isopropylphenyl) phosphate, 1 g

sc-498921
1 g
$214.00

Tris(4-isopropylphenyl) phosphate, 25 g

sc-498921A
25 g
$418.00

Hi, Can you let me know what the purity of Tris(4-isopropylphenyl) phosphate (sc-498921) is?

Asked by: Chu SG
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot. Please call us directly at (800) 457-3801 option 2, email scbt@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2021-08-25
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Rated 1 out of 5 by from this product is a mixture of isomers!!!no point or place on the product webpage indicates anything other than the 4--isopropyl isomer is present. the structure given for the product is shown only as the 4-isomer.additionally there is no mention of the presence of other isomers nor is there mention of technical grade of the material. over the last 20 yrs i have purchased many technical grade items. those were clearly shown on the product order page. had santa cruz bothered to list that property of the material, i would not have placed the order.
Date published: 2018-01-02
Rated 1 out of 5 by from T4IPPP purityDepended on my LC-MS analysis the product purity has a problem. There are a lot of isomers in the product.
Date published: 2016-11-23
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Tris(4-isopropylphenyl) phosphate is rated 1.0 out of 5 by 2.
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