Date published: 2025-10-2

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Tris(2-butoxyethyl) phosphate (CAS 78-51-3)

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Alternate Names:
Phosphoric acid tris(2-butoxyethyl) ester
Application:
Tris(2-butoxyethyl) phosphate is an organic flame retardant
CAS Number:
78-51-3
Purity:
≥93%
Molecular Weight:
398.47
Molecular Formula:
C18H39O7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tris(2-butoxyethyl) phosphate exhibits PXR agnostic activity and is an organic flame retardant.


Tris(2-butoxyethyl) phosphate (CAS 78-51-3) References

  1. Multiple bio-analytical methods to reveal possible molecular mechanisms of developmental toxicity in zebrafish embryos/larvae exposed to tris(2-butoxyethyl) phosphate.  |  Han, Z., et al. 2014. Aquat Toxicol. 150: 175-81. PMID: 24685621
  2. Tris(2-butoxyethyl)phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in chicken embryos.  |  Egloff, C., et al. 2014. Toxicol Appl Pharmacol. 279: 303-310. PMID: 24998971
  3. Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio).  |  Ma, Z., et al. 2016. Chemosphere. 144: 1920-7. PMID: 26547027
  4. Differential modulation of expression of nuclear receptor mediated genes by tris(2-butoxyethyl) phosphate (TBOEP) on early life stages of zebrafish (Danio rerio).  |  Ma, Z., et al. 2015. Aquat Toxicol. 169: 196-203. PMID: 26562049
  5. Effects of tris(2-butoxyethyl) phosphate exposure on endocrine systems and reproduction of zebrafish (Danio rerio).  |  Kwon, B., et al. 2016. Environ Pollut. 214: 568-574. PMID: 27131816
  6. Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish.  |  Liu, Y., et al. 2017. Aquat Toxicol. 191: 17-24. PMID: 28772162
  7. Tris (2-butoxyethyl) phosphate affects motor behavior and axonal growth in zebrafish (Danio rerio) larvae.  |  Jiang, F., et al. 2018. Aquat Toxicol. 198: 215-223. PMID: 29558706
  8. Tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells.  |  Ren, G., et al. 2017. Toxicol Res (Camb). 6: 902-911. PMID: 30090552
  9. Effects of environmentally relevant concentrations of tris (2-butoxyethyl) phosphate on growth and transcription of genes involved in the GH/IGF and HPT axes in zebrafish (Danio rerio).  |  Zeng, X., et al. 2018. Chemosphere. 212: 376-384. PMID: 30149310
  10. Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations.  |  Huang, Y., et al. 2019. Chemosphere. 218: 449-457. PMID: 30497028
  11. Biological responses of Eisenia fetida towards the exposure and metabolism of tris (2-butoxyethyl) phosphate.  |  Wu, X., et al. 2022. Sci Total Environ. 811: 152285. PMID: 34933047
  12. Toxicity of di-2-ethylhexyl phthalate and tris (2-butoxyethyl) phosphate to a tropical micro-crustacean (Ceriodaphnia cornuta) is higher in Mekong River water than in standard laboratory medium.  |  Dao, TS., et al. 2022. Environ Sci Pollut Res Int. 29: 39777-39789. PMID: 35113371
  13. Exposure to tris(2-butoxyethyl) phosphate induces abnormal sperm morphology and testicular histopathology in male rats.  |  Pan, HY., et al. 2022. Ecotoxicol Environ Saf. 241: 113718. PMID: 35660377

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tris(2-butoxyethyl) phosphate, 100 g

sc-237373
100 g
$51.00