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Triptorelin Acetate (CAS 140194-24-7)

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Alternate Names:
6-D-Tryptophan Luteinizing Hormone-Releasing Factor (Swine) Acetate; BIM 21003C; (D-Trp6)-LHRH
Application:
Triptorelin Acetate is decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH)
CAS Number:
140194-24-7
Molecular Weight:
1371.52
Molecular Formula:
C64H82N18O13•C2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triptorelin acetate, by targeting and activating the receptor specifically recognized for its interaction within the hypothalamus, plays a pivotal role in modulating the endocrine system′s regulatory mechanisms. Upon binding to this receptor, it sets off a cascade of biological events that culminate in the enhanced secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by the anterior pituitary gland. This action not only underscores its significance in studies related to the regulation of the reproductive axis but also in exploring the intricate feedback loops that govern hormonal balance within organisms.


Triptorelin Acetate (CAS 140194-24-7) References

  1. Increased prevalence of gestational diabetes mellitus in in vitro fertilization pregnancies inadvertently conceived during treatment with long-acting triptorelin acetate.  |  Mayer, A., et al. 2005. Fertil Steril. 84: 789-92. PMID: 16169427
  2. Formulation and evaluation of an in situ gel forming system for controlled delivery of triptorelin acetate.  |  Abashzadeh, Sh., et al. 2011. Eur J Pharm Sci. 44: 514-21. PMID: 21946260
  3. Pelvic adhesion and gonadotropin-releasing hormone analogue: effects of triptorelin acetate depot on coagulation and fibrinolytic activities.  |  Di Nardo, MA., et al. 2012. Reprod Sci. 19: 615-22. PMID: 22344729
  4. Comparison of dienogest versus triptorelin acetate in premenopausal women with adenomyosis: a prospective clinical trial.  |  Fawzy, M. and Mesbah, Y. 2015. Arch Gynecol Obstet. 292: 1267-71. PMID: 25990480
  5. Evaluation of an intravaginal triptorelin acetate gel for inducing ovulation in mares.  |  Sinclair, CD., et al. 2017. J Anim Sci. 95: 3631-3638. PMID: 28805910
  6. Clinical evaluation of laparoscopic surgery combined with triptorelin acetate in patients with endometriosis and infertility.  |  Xue, H., et al. 2018. Pak J Med Sci. 34: 1064-1069. PMID: 30344551
  7. Efficacy and Safety of gonadotropin-releasing hormone (GnRH) Agonists Triptorelin Acetate and Cetrorelix Acetate in Assisted Reproduction.  |  Jiang, J., et al. 2018. Med Sci Monit. 24: 7996-8000. PMID: 30405094
  8. Comparison of triptorelin acetate vs triptorelin pamoate in the treatment of Central precocious puberty (CPP): a retrospective study.  |  Lasorella, S., et al. 2020. Gynecol Endocrinol. 36: 338-340. PMID: 31441342
  9. Single injection of triptorelin or buserelin acetate in saline solution induces ovulation in mares the same as a single injection of hCG.  |  Dordas-Perpinyà, M., et al. 2020. Reprod Domest Anim. 55: 374-383. PMID: 31930759
  10. Triptorelin Acetate 
(Veterinary Medicinal Products).  |  ,. 2016. Food Saf (Tokyo). 4: 173-174. PMID: 32231921
  11. Relapse after conservative surgery combined with triptorelin acetate versus conservative surgery only in women with focal adenomyosis: study protocol for a multicenter, prospective, randomized controlled trial.  |  Wang, W., et al. 2020. Trials. 21: 364. PMID: 32345377
  12. Comparison of two different GnRH analogs' impact on final height in girls with early puberty: Triptorelin acetate vs. leuprolide acetate.  |  Aka, S., et al. 2020. Acta Endocrinol (Buchar). 16: 402-408. PMID: 34084230
  13. Sustained In-Vivo Release of Triptorelin Acetate from a Biodegradable Silica Depot: Comparison to Pamorelin® LA.  |  Forsback, AP., et al. 2021. Nanomaterials (Basel). 11: PMID: 34208450
  14. Evaluation of Hypersensitivity Reactions with Leuprolide Acetate and Triptorelin Acetate in Children.  |  Metbulut, AP., et al. 2021. Indian J Endocrinol Metab. 25: 527-531. PMID: 35355908
  15. Triptorelin acetate administration in early pregnancy: case reports and review of the literature.  |  Chardonnens, D., et al. 1998. Eur J Obstet Gynecol Reprod Biol. 80: 143-9. PMID: 9846657

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triptorelin Acetate, 10 mg

sc-391254
10 mg
$250.00