Tripolin A (CAS 1148118-92-6)
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Tripolin A is a specific non-ATP competitive Aurora A kinase inhibitor. Tripolin A reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase. Tripolin A is a specialized abrasive powder renowned for its efficacy in polishing and cleansing metals. This composite blend comprises aluminum oxide, silicon dioxide, and other compounds, providing it with a potent rust, oxidation, and tarnish removal ability on various metals. The combination of silicon dioxide and aluminum oxide imparts remarkable hardness to the powder, while the inclusion of iron oxide contributes to its dark hue. Moreover, Tripolin A finds utility in the fabrication of abrasive tools, including grinding wheels and honing stones.
Tripolin A (CAS 1148118-92-6) References
- Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules. | Kesisova, IA., et al. 2013. PLoS One. 8: e58485. PMID: 23516487
- Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma. | Chen, Q., et al. 2020. BMC Cancer. 20: 372. PMID: 32357862
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tripolin A, 1 mg | sc-396525 | 1 mg | $104.00 | |||
Tripolin A, 5 mg | sc-396525A | 5 mg | $400.00 |