Molecular structure of Trimethylamine N-oxide dihydrate, CAS Number: 62637-93-8
Trimethylamine N-oxide dihydrate (CAS 62637-93-8)
Alternate Names:
TMANO
CAS Number:
62637-93-8
Purity:
≥98%
Molecular Weight:
111.14
Molecular Formula:
C3H9NO•2H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Trimethylamine N-oxide (TMAO) dihydrate is an oxidant for the catalytic OsO4 cis-hydroxylation of hindered olefins. It is used in the preparation of the unstable, crystalline anhydrous compound. In the laboratory, TMAO dihydrate is used to stabilize proteins and other biomolecules by preventing them from denaturing or losing their shape when exposed to changes in temperature, pH, or other environmental factors. This makes it useful in many biochemical and biophysical experiments, including protein crystallography and NMR spectroscopy.
Trimethylamine N-oxide dihydrate (CAS 62637-93-8) References
- No effect of trimethylamine N-oxide on the internal dynamics of the protein native fold. | Gonnelli, M. and Strambini, GB. 2001. Biophys Chem. 89: 77-85. PMID: 11246747
- Determination of trimethylamine and related aliphatic amines in human urine by head-space gas chromatography. | Zhang, AQ., et al. 1992. J Chromatogr. 584: 141-5. PMID: 1484098
- Complex formation in aqueous trimethylamine-N-oxide (TMAO) solutions. | Hunger, J., et al. 2012. J Phys Chem B. 116: 4783-95. PMID: 22458563
- Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats. | Ufnal, M., et al. 2014. Can J Cardiol. 30: 1700-5. PMID: 25475471
- Trimethylamine N-oxide (TMAO) is a counteracting solute of benzyl alcohol for multi-dose formulation of immunoglobulin. | Yoshizawa, S., et al. 2018. Int J Biol Macromol. 107: 984-989. PMID: 28939518
- Terpolymers from Borane-Initiated Copolymerization of Triphenyl Arsonium and Sulfoxonium Ylides: An Unexpected Light Emission. | Wang, D. and Hadjichristidis, N. 2019. Angew Chem Int Ed Engl. 58: 6295-6299. PMID: 30807683
- Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states. | Liang, WG., et al. 2021. Structure. 29: 709-720.e3. PMID: 33378640
- A Modular Strategy for Expanding Electron-Sink Capacity in Noncanonical Cluster Assemblies. | Mai, Y., et al. 2021. Inorg Chem. 60: 17733-17743. PMID: 34748324
- Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF. | Tao, H., et al. 2022. Nat Commun. 13: 95. PMID: 35013177
- Oxygenated Cyclopentenones via the Pauson-Khand Reaction of Silyl Enol Ether Substrates. | Shaw, P., et al. 2022. Org Lett. 24: 2750-2755. PMID: 35377671
- Polycentric binding in complexes of trimethylamine-N-oxide with dihalogens. | Zarechnaya, OM., et al. 2021. RSC Adv. 11: 6131-6145. PMID: 35423161
- New Insights of OLFM2 and OLFM4 in Gut-Liver Axis and Their Potential Involvement in Nonalcoholic Fatty Liver Disease. | Bertran, L., et al. 2022. Int J Mol Sci. 23: PMID: 35806447
- Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A. | Kurup, HM., et al. 2022. Biochemistry. 61: 2568-2578. PMID: 36302365
- Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. | Cho, G., et al. 2023. Nucleic Acids Res. 51: 1971-1983. PMID: 36762482
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trimethylamine N-oxide dihydrate, 25 g | sc-296626 | 25 g | $87.00 | |||
Trimethylamine N-oxide dihydrate, 500 g | sc-296626A | 500 g | $713.00 |