TRIM16 Antibody (5-RY8): sc-135586
- TRIM16 Antibody (5-RY8) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant TRIM16 protein of human origin
- recommended for detection of TRIM16 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TRIM16 Antibody (5-RY8). This work is in progress.
TRIM16 Antibody (5-RY8) is a mouse monoclonal IgG2a antibody that detects TRIM16 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TRIM16, also known as Estrogen-responsive B box protein (EBBP), is a 564 amino acid protein belonging to the tripartite motif (TRIM) family, characterized by a conserved TRIM domain that includes a coiled-coil region, two B box-type zinc fingers, and one B30.2/SPRY domain. TRIM16 plays a crucial role in various cellular processes, including the regulation of keratinocyte differentiation, particularly in basal keratinocytes, where TRIM16 expression is vital for maintaining skin homeostasis. Notably, TRIM16 is highly expressed in reproductive tissues such as the testis and ovary, as well as in the small intestine, colon, placenta, heart, skeletal muscle, and mammary gland, with TRIM16 expression levels being significantly higher in fetal tissues compared to adults. TRIM16′s ability to influence histone acetylation in retinoid-resistant cancer cells suggests TRIM16′s potential as a therapeutic target, making anti-TRIM16 antibody (5-RY8) an essential tool for researchers investigating TRIM16′s role in cancer biology and differentiation processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRIM16 Antibody (5-RY8) | sc-135586 | 100 µg/ml | $333.00 |