Molecular structure of Triisopropylsilane, CAS Number: 6485-79-6
Triisopropylsilane (CAS 6485-79-6)
Alternate Names:
TIS; Tris-isopropylsilane
Application:
Triisopropylsilane is a highly selective reducing agent which can be used to prepare anti-1,2-diols.
CAS Number:
6485-79-6
Purity:
≥98%
Molecular Weight:
158.36
Molecular Formula:
C9H22Si
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Triisopropylsilane is a reducing agent. It functions as a strong and selective reducing agent for the reduction of various functional groups, such as ketones, esters, and amides. Its mechanism of action involves the transfer of a hydride ion to the substrate, leading to the formation of the corresponding alcohol or amine. Triisopropylsilane is particularly useful in the reduction of sensitive functional groups, such as acid chlorides and epoxides, due to its mild reaction conditions.
Triisopropylsilane (CAS 6485-79-6) References
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- Reduction of cysteine-S-protecting groups by triisopropylsilane. | Ste Marie, EJ. and Hondal, RJ. 2018. J Pept Sci. 24: e3130. PMID: 30353614
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- Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods. | Wester, A., et al. 2021. Amino Acids. 53: 1455-1466. PMID: 34410506
- Total synthesis of diazaquinomycins H and J using double Knorr cyclization in the presence of triisopropylsilane. | Prior, AM. and Sun, D. 2019. RSC Adv. 9: 1759-1771. PMID: 35516148
- S-Protected Cysteine Sulfoxide-Enabled Tryptophan-Selective Modification with Application to Peptide Lipidation. | Kobayashi, D., et al. 2022. ACS Med Chem Lett. 13: 1125-1130. PMID: 35859873
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Triisopropylsilane, 10 g | sc-296622 | 10 g | $36.00 | |||
Triisopropylsilane, 50 g | sc-296622A | 50 g | $78.00 |