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Triflupromazine hydrochloride (CAS 1098-60-8)

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Alternate Names:
N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine hydrochloride
Application:
Triflupromazine hydrochloride is a neurology research compound
CAS Number:
1098-60-8
Molecular Weight:
388.88
Molecular Formula:
C18H19F3N2S•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triflupromazine hydrochloride is a chemical that is studied in various research applications. In analytical chemistry, this compound is often used as a reference material to develop and validate analytical methods such as chromatography and spectroscopy. Due to its structural features, which include a tricyclic ring system with fluorine atoms and a basic nitrogen that can form a hydrochloride salt, Triflupromazine hydrochloride is a subject in the study of physicochemical properties like solubility, stability, and crystallization. Chemists may also explore the compound′s reactivity in synthetic pathways for the preparation of structurally related compounds. In the field of materials science, Triflupromazine hydrochloride can be used to investigate the interaction of organic molecules with inorganic surfaces, which is relevant to the development of sensor technologies and the study of molecule-surface interactions. The compound′s characteristic absorbance and fluorescence properties make it suitable for research in the development of detection systems and the study of photophysical behavior.


Triflupromazine hydrochloride (CAS 1098-60-8) References

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  2. Some effects of triflupromazine hydrochloride on goats.  |  JHA, SK., et al. 1961. Am J Vet Res. 22: 915-20. PMID: 13790062
  3. Use of triflupromazine hydrochloride for control of emetic reactions to nitrogen mustard therapy.  |  BLAKE, JM. and HAYFORD, FC. 1960. N Y State J Med. 60: 2114-7. PMID: 13801261
  4. Comparative short-term evaluation of triflupromazine hydrochloride, chlorpromazine hydrochloride, and placebo in acutely disturbed patients.  |  MORGENSTERN, FV., et al. 1960. N Y State J Med. 60: 254-8. PMID: 14424132
  5. Accidental chemical poisonings. Triflupromazine hydrochloride, aspirin, and phosphorus poisonings.  |  JACOBZINER, H. and RAYBIN, HW. 1962. N Y State J Med. 62: 2847-9. PMID: 14450765
  6. 19F NMR spectroscopic study on the binding of triflupromazine to bovine and human serum albumins.  |  Kitamura, K., et al. 2004. J Pharm Biomed Anal. 36: 411-4. PMID: 15496337
  7. Solubility and pKa determination of six structurally related phenothiazines.  |  Domańska, U., et al. 2011. Int J Pharm. 421: 135-44. PMID: 21983455
  8. [Studies on the stability of injectable solutions of some phenothiazines. Part 1: Effects of pH and buffer systems].  |  Ammar, HO., et al. 1975. Pharmazie. 30: 368-9. PMID: 240174
  9. Phenothiazines solution complexity - Determination of pKa and solubility-pH profiles exhibiting sub-micellar aggregation at 25 and 37°C.  |  Pobudkowska, A., et al. 2016. Eur J Pharm Sci. 93: 163-76. PMID: 27449396
  10. Haemodynamic and blood gas changes in buffaloes (Bubalus bubalis) in the supine position following thiopentone anaesthesia with premedication.  |  Peshin, PK., et al. 1987. Vet Res Commun. 11: 1-7. PMID: 3576966
  11. High-performance liquid chromatographic determination of triflupromazine hydrochloride in tablets and injections.  |  Shirsat, PH. and Clarke, G. 1980. Analyst. 105: 823-6. PMID: 7416490
  12. Determination of nortriptyline in sugar-coated tablets by high-performance liquid chromatography.  |  Salmon, JR. and Wood, PR. 1976. Analyst. 101: 611-5. PMID: 970649

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triflupromazine hydrochloride, 100 mg

sc-251335
100 mg
$124.00

Triflupromazine hydrochloride, 250 mg

sc-251335A
250 mg
$250.00