Date published: 2025-10-14

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Trifluoroacetaldehyde methyl hemiacetal (CAS 431-46-9)

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Application:
Trifluoroacetaldehyde methyl hemiacetal is a stable source of trifluoroacetaldehyde
CAS Number:
431-46-9
Molecular Weight:
130.06
Molecular Formula:
C3H5F3O2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trifluoroacetaldehyde methyl hemiacetal is a stable source of trifluoroacetaldehyde. It is characterized by a single carbon-oxygen bond. It is highly reactive and is often used in laboratory experiments and applications.


Trifluoroacetaldehyde methyl hemiacetal (CAS 431-46-9) References

  1. Carbinolamines, imines, and oxazolidines from fluorinated propranolol analogs. (19)F NMR and mass spectral characterization and evidence for formation as intermediates in cytochrome P450-catalyzed N-dealkylation.  |  Upthagrove, AL. and Nelson, WL. 2001. Drug Metab Dispos. 29: 1114-22. PMID: 11454730
  2. Fluorination-free synthesis of a 4,4-difluoro-3,3-dimethylproline derivative.  |  Chen, L., et al. 2006. J Org Chem. 71: 5468-73. PMID: 16839124
  3. Enantioselective Friedel-Crafts reaction of indoles with trifluoroacetaldehyde catalyzed by Cinchona alkaloids.  |  Borkin, DA., et al. 2011. Chirality. 23: 612-6. PMID: 21748810
  4. One-pot preparation of trifluoromethylated homoallylic N-acylhydrazines or α-methylene-γ-lactams from acylhydrazines, trifluoroacetaldehyde methyl hemiacetal, allyl bromide and tin.  |  Du, G., et al. 2016. Org Biomol Chem. 14: 1492-500. PMID: 26690835

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trifluoroacetaldehyde methyl hemiacetal, 5 g

sc-264469B
5 g
$54.00

Trifluoroacetaldehyde methyl hemiacetal, 10 g

sc-264469
10 g
$112.00

Trifluoroacetaldehyde methyl hemiacetal, 25 g

sc-264469A
25 g
$128.00