Date published: 2026-4-4

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Triethylammonium Acetate (CAS 5204-74-0)

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CAS Number:
5204-74-0
Molecular Weight:
161.24
Molecular Formula:
C8H19NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triethylammonium acetate is an ionic compound known as a quaternary ammonium salt, consisting of a positively charged nitrogen atom surrounded by four organic groups. This compound possesses strong nucleophilic properties, enabling its use as a catalyst for diverse organic reactions, such as carboxylic acid esterification. Additionally, it finds application as a versatile buffer in biochemical and analytical experiments due to its ability to maintain a stable pH across a broad range of concentrations. Furthermore, triethylammonium acetate serves as an effective solubilizing agent for various compounds, including proteins, peptides, and nucleic acids.


Triethylammonium Acetate (CAS 5204-74-0) References

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  5. Selective anomeric acetylation of unprotected sugars in water.  |  Lim, D. and Fairbanks, AJ. 2017. Chem Sci. 8: 1896-1900. PMID: 28553480
  6. Diarylpyrazole Ligated Dihydropyrimidine Hybrids as Potent Non-Classical Antifolates and Their Efficacy Against Plasmodium falciparum.  |  Bhatt, JD., et al. 2017. Arch Pharm (Weinheim). 350: PMID: 28796406
  7. Enhancing the Mass Spectrometry Sensitivity for Oligonucleotide Detection by Organic Vapor Assisted Electrospray.  |  Weng, G., et al. 2017. Anal Chem. 89: 10256-10263. PMID: 28872850
  8. Analysis of oligonucleotides by ion-pairing hydrophilic interaction liquid chromatography/electrospray ionization mass spectrometry.  |  Gong, L. 2017. Rapid Commun Mass Spectrom. 31: 2125-2134. PMID: 28972295
  9. Ion-Pairing with Triethylammonium Acetate Improves Solid-Phase Extraction of ADP-Ribosylated Peptides.  |  McPherson, RL., et al. 2020. J Proteome Res. 19: 984-990. PMID: 31859514
  10. Structural Features of Triethylammonium Acetate through Molecular Dynamics.  |  Bodo, E. 2020. Molecules. 25: PMID: 32245229
  11. Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes.  |  Chu, H., et al. 2022. Anal Chem. 94: 758-767. PMID: 34932315
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triethylammonium Acetate, 1 L

sc-505910
1 L
$582.00