Trichloromethiazide (CAS 133-67-5)
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Trichlormethiazide (TCMZ) is a thiazide diuretic known for its role in promoting sodium and water excretion by inhibiting the Na+/K+-ATPase enzyme in the kidneys. This action impedes sodium reabsorption, leading to increased urine production. Additionally, it affects the renin-angiotensin-aldosterone system by blocking the angiotensin-converting enzyme (ACE), which contributes to its ability to decrease aldosterone production. The effectiveness and specific biochemical pathways of Trichloromethiazide have been explored through extensive in vivo and in vitro research. Studies conducted in live organisms have shed light on its capacity to reduce sodium reabsorption and enhance water excretion, while laboratory experiments have further confirmed its inhibitory effects on critical enzymes involved in body fluid and electrolyte regulation.
Trichloromethiazide (CAS 133-67-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Trichloromethiazide, 10 g | sc-296609 | 10 g | $245.00 |