Date published: 2026-5-22

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Triacetyl-β-cyclodextrin (CAS 23739-88-0)

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Alternate Names:
β-Cyclodextrin heneicosaacetate
Application:
Triacetyl-β-cyclodextrin is a synthetic reagent
CAS Number:
23739-88-0
Molecular Weight:
2017.75
Molecular Formula:
C84H112O56
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triacetyl-β-cyclodextrin, a chemically modified form of β-cyclodextrin, is extensively used in scientific research due to its enhanced hydrophobicity compared to its native counterpart. This compound is particularly valuable for studying molecular encapsulation phenomena, where its cavity provides a hydrophobic microenvironment capable of hosting various non-polar molecules. Such research is fundamental in the fields of supramolecular chemistry and material science, where Triacetyl-β-cyclodextrin is used to investigate the stabilization of volatile compounds, improve the solubility of poorly soluble substances, and control the release of encapsulated agents in applications like food flavoring and fragrance delivery. Furthermore, its utility extends to environmental science, where it aids in the capture and removal of pollutants from water, contributing to the development of innovative filtration technologies. These studies also provide insights into the design of new polymer matrices for industrial use, exploring how the inclusion complexes formed by Triacetyl-β-cyclodextrin can enhance material properties such as durability and resistance to environmental stressors. This chemical thereby plays a crucial role in advancing our understanding of host-guest chemistry and its application in developing advanced materials and technologies.


Triacetyl-β-cyclodextrin (CAS 23739-88-0) References

  1. Effect of the hydrophobic nature of triacetyl-beta-cyclodextrin on the complexation with nicardipine hydrochloride: physicochemical and dissolution properties of the kneaded and spray-dried complexes.  |  Fernandes, CM. and Veiga, FJ. 2002. Chem Pharm Bull (Tokyo). 50: 1597-602. PMID: 12499598
  2. Multimodal molecular encapsulation of nicardipine hydrochloride by beta-cyclodextrin, hydroxypropyl-beta-cyclodextrin and triacetyl-beta-cyclodextrin in solution. Structural studies by 1H NMR and ROESY experiments.  |  Fernandes, CM., et al. 2003. Eur J Pharm Sci. 18: 285-96. PMID: 12694880
  3. Sustained-release matrix tablets of metformin hydrochloride in combination with triacetyl-beta-cyclodextrin.  |  Corti, G., et al. 2008. Eur J Pharm Biopharm. 68: 303-9. PMID: 17616379
  4. Physical-chemical characterization of binary systems of metformin hydrochloride with triacetyl-beta-cyclodextrin.  |  Corti, G., et al. 2007. J Pharm Biomed Anal. 45: 480-6. PMID: 17822867
  5. High-pressure NMR characterization of triacetyl-beta-cyclodextrin in supercritical carbon dioxide.  |  Ivanova, GI., et al. 2009. Magn Reson Chem. 47: 133-41. PMID: 19012270
  6. Pharmacokinetic delivery and metabolizing rate of nicardipine incorporated in hydrophilic and hydrophobic cyclodextrins using two-compartment mathematical model.  |  Shityakov, S. and Förster, C. 2013. ScientificWorldJournal. 2013: 131358. PMID: 24391458
  7. Effect of β-Cyclodextrin on Physicochemical Properties of an Ionic Liquid Electrolyte Composed of N-Methyl-N-Propylpyrrolidinium bis(trifluoromethylsulfonyl)amide.  |  Suzuki, M., et al. 2019. Front Chem. 7: 90. PMID: 30842943
  8. Novel Carbon/PEDOT/PSS-Based Screen-Printed Biosensors for Acetylcholine Neurotransmitter and Acetylcholinesterase Detection in Human Serum.  |  Ashmawy, NH., et al. 2019. Molecules. 24: PMID: 31003551
  9. Enhanced Nanoencapsulation of Sepiapterin within PEG-PCL Nanoparticles by Complexation with Triacetyl-Beta Cyclodextrin.  |  Kuplennik, N. and Sosnik, A. 2019. Molecules. 24: PMID: 31357400
  10. Processing triacetyl-β-cyclodextrin in the liquid phase using supercritical CO2  |  Nunes, A. V. M., Almeida, A. P. C., Marques, S. R., de Sousa, A. S., Casimiro, T., & Duarte, C. M. 2010. The Journal of Supercritical Fluids. 54(3): 357-361.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triacetyl-β-cyclodextrin, 10 g

sc-237245
10 g
$126.00