Treponema pallidum Antibody (Tr33): sc-52261

Treponema pallidum Antibody (Tr33) is a mouse monoclonal IgG1 antibody that detects Treponema pallidum by western blotting (WB). Treponema pallidum is a Gram-negative spirochaete bacterium known for its unique structure, which includes a thin cell wall and periplasmic flagella that enable its characteristic corkscrew motility. This motility is crucial for the bacterium′s ability to navigate through the viscous environments of host tissues, facilitating invasion and colonization. A streamlined genome, consisting of only 1.14 million base pairs, reflects evolutionary adaptation to the complex mammalian host environment, where Treponema pallidum relies on host-derived nutrients due to limited metabolic capabilities. Treponema pallidum′s ability to evade host immune response and transmission through sexual contact or from mother to fetus during pregnancy underscores the importance of understanding its biology, particularly in the context of diseases such as syphilis and congenital syphilis. Anti-Treponema pallidum antibody (Tr33) is an essential tool for researchers studying this pathogen, providing valuable insights into its structure and function.

The preferred Treponema pallidum antibody is Treponema pallidum Antibody (2121): sc-58204.