trans-Triprolidine hydrochloride is a potent Histamine H1 receptor antagonist.
Merck Index 12 9877. Hill (1990) Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45.
Soluble in water (100 mg/ml), alcohol (1:1.5), and chloroform (1:<1).
Store at 4° C
462° C (dec.) at 760 mmHg
n20D ~1.59 (Predicted)
Plasmodium falciparum 7G8 : IC50 = 2 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Tabarean IV (PubMed ID: 23808378) determinedTabarean IV (PubMed ID: 23808378) determined that trans-Triprolidine hydrochloride antagonized the activation by histamine of H1 receptors in hypothalamic neurons in mice. -SCBT Publication Review
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