Date published: 2026-2-13

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trans-Nonachlor (CAS 39765-80-5)

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CAS Number:
39765-80-5
Molecular Weight:
444.22
Molecular Formula:
C10H5Cl9
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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trans-Nonachlor is a specific isomer of nonachlor, which is a chlorinated hydrocarbon. Its structure is characterized by the arrangement of chlorine atoms, which influences its physical and chemical properties. Due to its nature as a chlorinated hydrocarbon, it may be used in toxicology studies to understand the impact of such compounds on health and the environment. Developing and validating analytical methods for the detection and quantification of trans-Nonachlor in environmental samples. Techniques like gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography (HPLC) are used.


trans-Nonachlor (CAS 39765-80-5) References

  1. trans-Nonachlor and cis-nonachlor toxicity in Sprague-Dawley rats: comparison with technical chlordane.  |  Bondy, GS., et al. 2000. Toxicol Sci. 58: 386-98. PMID: 11099650
  2. Effects of cis-nonachlor, trans-nonachlor and chlordane on the immune system of Sprague-Dawley rats following a 28-day oral (gavage) treatment.  |  Tryphonas, H., et al. 2003. Food Chem Toxicol. 41: 107-18. PMID: 12453735
  3. Toxicity of trans-nonachlor to Sprague-Dawley rats in a 90-day feeding study.  |  Bondy, G., et al. 2004. Food Chem Toxicol. 42: 1015-27. PMID: 15110111
  4. Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys.  |  Trabert, B., et al. 2012. Environ Health Perspect. 120: 478-82. PMID: 21975279
  5. Is meconium useful to predict fetal exposure to organochlorines and hydroxylated PCBs?  |  Veyhe, AS., et al. 2013. Environ Sci Process Impacts. 15: 1490-500. PMID: 23828374
  6. The association of serum trans-nonachlor levels with atherosclerosis.  |  Mangum, LC., et al. 2016. J Toxicol Environ Health A. 79: 210-20. PMID: 26953872
  7. Trans-nonachlor decreases miR-141-3p levels in human melanocytes in vitro promoting melanoma cell characteristics and shows a multigenerational impact on miR-8 levels in Drosophila.  |  Verrando, P., et al. 2016. Toxicology. 368-369: 129-141. PMID: 27616325
  8. 'Trans-nonachlor increases extracellular free fatty acid accumulation and de novo lipogenesis to produce hepatic steatosis in McArdle-RH7777 cells'.  |  Howell, GE., et al. 2018. Toxicol In Vitro. 50: 285-292. PMID: 29654899
  9. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes.  |  Howell, GE., et al. 2018. Environ Toxicol. 33: 962-971. PMID: 29964320
  10. Development of Biomonitoring Equivalents for chlordane and toxaphene with application to the general Canadian population.  |  Singh, K., et al. 2019. Regul Toxicol Pharmacol. 106: 262-269. PMID: 31103637
  11. Association of Maternal Exposure to Persistent Organic Pollutants in Early Pregnancy With Fetal Growth.  |  Ouidir, M., et al. 2020. JAMA Pediatr. 174: 149-161. PMID: 31886849
  12. Associations between prenatal exposure to organochlorine pesticides and thyroid hormone levels in mothers and infants: The Hokkaido study on environment and children's health.  |  Yamazaki, K., et al. 2020. Environ Res. 189: 109840. PMID: 32979988
  13. Prenatal exposure to endocrine disrupting chemical mixtures and infant birth weight: A Bayesian analysis using kernel machine regression.  |  Hu, JMY., et al. 2021. Environ Res. 195: 110749. PMID: 33465343
  14. Metabolomic profiling to assess the effects of chlordanes and its bioaccumulation characteristics in chicken embryo.  |  Liu, X., et al. 2022. Chemosphere. 308: 136580. PMID: 36155011

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-Nonachlor, 25 mg

sc-258274
25 mg
$168.00