Date published: 2025-9-14

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trans-Cinnamic acid (CAS 140-10-3)

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Alternate Names:
trans-3-Phenylacrylic acid
Application:
trans-Cinnamic acid is A biochemical used to establish library of phenolic compounds.
CAS Number:
140-10-3
Purity:
≥99%
Molecular Weight:
148.16
Molecular Formula:
C9H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trans-Cinnamic acid functions as a precursor in the biosynthesis of a variety of products, including flavonoids, lignans, and stilbenes. It acts as a substrate for enzymes involved in the production of these compounds, serving as a starting point for the synthesis of complex molecules. At the molecular level, trans-Cinnamic acid undergoes enzymatic reactions, leading to the formation of diverse secondary metabolites with potential biological activities. Its mechanism of action involves participating in enzymatic processes that lead to the generation of structurally diverse products.


trans-Cinnamic acid (CAS 140-10-3) References

  1. Structure-activity relationships of trans-cinnamic acid derivatives on alpha-glucosidase inhibition.  |  Adisakwattana, S., et al. 2004. Bioorg Med Chem Lett. 14: 2893-6. PMID: 15125954
  2. The allelochemical trans-cinnamic acid stimulates salicylic acid production and galactose pathway in maize leaves: A potential mechanism of stress tolerance.  |  Araniti, F., et al. 2018. Plant Physiol Biochem. 128: 32-40. PMID: 29753136
  3. Antimicrobial activity of trans-cinnamic acid and commonly used antibiotics against important fish pathogens and nonpathogenic isolates.  |  Yilmaz, S., et al. 2018. J Appl Microbiol.. PMID: 30179290
  4. Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes.  |  Kang, NH., et al. 2019. Nutrients. 11: PMID: 30857158
  5. trans-Cinnamic acid-induced leaf expansion involves an auxin-independent component.  |  Kurepa, J. and Smalle, JA. 2019. Commun Integr Biol. 12: 78-81. PMID: 31143367
  6. Microwave-Assisted Synthesis of trans-Cinnamic Acid for Highly Efficient Removal of Copper from Aqueous Solution.  |  Dávila-Guzmán, NE., et al. 2020. ACS Omega. 5: 317-326. PMID: 31956778
  7. Anti-obesity effect of trans-cinnamic acid on HepG2 cells and HFD-fed mice.  |  Wang, Z., et al. 2020. Food Chem Toxicol. 137: 111148. PMID: 31982449
  8. Effect of trans-cinnamic acid and p-coumaric acid on fibroblast motility: a pilot comparative study of in silico lipophilicity measure.  |  Viana, RDS., et al. 2021. Nat Prod Res. 35: 5872-5878. PMID: 32713206
  9. trans-Cinnamic acid, but not p-coumaric acid or methyl cinnamate, induces fibroblast migration through PKA- and p38-MAPK signalling pathways.  |  Aquino, FLT., et al. 2021. J Tissue Viability. 30: 363-371. PMID: 34052086
  10. Production of trans-cinnamic acid by whole-cell bioconversion from L-phenylalanine in engineered Corynebacterium glutamicum.  |  Son, J., et al. 2021. Microb Cell Fact. 20: 145. PMID: 34303376
  11. Production of Cinnamaldehyde through Whole-Cell Bioconversion from trans-Cinnamic Acid Using Engineered Corynebacterium glutamicum.  |  Son, J., et al. 2022. J Agric Food Chem. 70: 2656-2663. PMID: 35102737
  12. Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer.  |  Badawi, NM., et al. 2022. Int J Nanomedicine. 17: 733-750. PMID: 35210772
  13. Short-Term Effects of Trans-Cinnamic Acid on the Metabolism of Zea mays L. Roots.  |  López-González, D., et al. 2023. Plants (Basel). 12: PMID: 36616318
  14. Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A.  |  Kang, C., et al. 2022. Pharmaceutics. 15: PMID: 36678670
  15. Structure-Activity Relationship (SAR) Study of trans-Cinnamic Acid and Derivatives on the Parasitic Weed Cuscuta campestris.  |  Moreno-Robles, A., et al. 2023. Plants (Basel). 12: PMID: 36840045

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-Cinnamic acid, 100 g

sc-251283
100 g
$31.00

trans-Cinnamic acid, 500 g

sc-251283A
500 g
$101.00

trans-Cinnamic acid, 2.5 kg

sc-251283B
2.5 kg
$403.00