trans-Abacavir Dihydrochloride (CAS 267668-71-3)
Alternate Names:
(1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride
Application:
trans-Abacavir Hydrochloride is the trans-isomer of Abacavir, a nucleoside reverse transcriptase inhibitor (NRTI)
CAS Number:
267668-71-3
Molecular Weight:
359.25
Molecular Formula:
C14H20Cl2N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
trans-Abacavir Hydrochloride is the trans-isomer of Abacavir [also called Ziagen (sc-338739)], a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme. trans-Abacavir Hydrochloride is an Abacavir USP impurity.
trans-Abacavir Dihydrochloride (CAS 267668-71-3) References
- Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes. | Krejcová, R., et al. 2000. Biochem Pharmacol. 60: 1907-13. PMID: 11108807
- Phosphonomethoxyalkyl analogs of nucleotides. | Holy, A. 2003. Curr Pharm Des. 9: 2567-92. PMID: 14529543
- Antiviral drugs in wastewater and surface waters: a new pharmaceutical class of environmental relevance? | Prasse, C., et al. 2010. Environ Sci Technol. 44: 1728-35. PMID: 20108960
- Phospholipidosis as a function of basicity, lipophilicity, and volume of distribution of compounds. | Hanumegowda, UM., et al. 2010. Chem Res Toxicol. 23: 749-55. PMID: 20356072
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
trans-Abacavir Dihydrochloride, 1 mg | sc-479376 | 1 mg | $430.00 |