Molecular structure of trans-4-Methylcyclohexylamine, CAS Number: 2523-55-9
trans-4-Methylcyclohexylamine (CAS 2523-55-9)
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Alternate Names:
trans-4-Methylcyclohexan-1-amine
CAS Number:
2523-55-9
Molecular Weight:
113.20
Molecular Formula:
C7H15N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Trans-4-Methylcyclohexylamine (4-MCHA) represents an aromatic amine, an organic compound with a cyclic structure consisting of a four-carbon ring and a methyl group attached to the nitrogen atom. Within scientific research, trans-4-Methylcyclohexylamine demonstrates a broad range of applications. It acts as a vital reagent in synthesizing various compounds, including peptides, proteins, and carbohydrates. Furthermore, it contributes to the synthesis of catalysts, including palladium, platinum, and ruthenium catalysts.
trans-4-Methylcyclohexylamine (CAS 2523-55-9) References
- Mammalian spermidine synthase--identification of cysteine residues and investigation of the putrescine binding site--. | Goda, H., et al. 2004. Biol Pharm Bull. 27: 1327-32. PMID: 15340214
- Control of spermidine and spermine levels in rat tissues by trans-4-methylcyclohexylamine, a spermidine-synthase inhibitor. | Kobayashi, M., et al. 2005. Biol Pharm Bull. 28: 569-73. PMID: 15802788
- The spermidine synthase of the malaria parasite Plasmodium falciparum: molecular and biochemical characterisation of the polyamine synthesis enzyme. | Haider, N., et al. 2005. Mol Biochem Parasitol. 142: 224-36. PMID: 15913804
- Inhibition of putrescine aminopropyltransferase influences rat liver regeneration. | Kobayashi, M., et al. 2006. Biol Pharm Bull. 29: 863-7. PMID: 16651710
- Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. | Dufe, VT., et al. 2007. J Mol Biol. 373: 167-77. PMID: 17822713
- Electrospray ionization and time-of-flight mass spectrometric method for simultaneous determination of spermidine and spermine. | Samejima, K., et al. 2007. Biol Pharm Bull. 30: 1943-6. PMID: 17917267
- Chemoprevention of B-cell lymphomas by inhibition of the Myc target spermidine synthase. | Forshell, TP., et al. 2010. Cancer Prev Res (Phila). 3: 140-7. PMID: 20103729
- [Identification of novel molecules regulating differentiation and hormone secretion and clarification of their functional mechanisms in pancreatic endocrine cells]. | Oka, T., et al. 2010. Yakugaku Zasshi. 130: 377-88. PMID: 20190522
- Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. | Ishii, I., et al. 2012. Amino Acids. 42: 619-26. PMID: 21809076
- Trans-4-methylcyclohexylamine, a potent new inhibitor of spermidine synthase. | Shirahata, A., et al. 1988. Chem Pharm Bull (Tokyo). 36: 3220-2. PMID: 3240528
- Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase. | He, Y., et al. 1995. J Biochem. 117: 824-9. PMID: 7592545
- Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases. | Beppu, T., et al. 1995. J Biochem. 117: 339-45. PMID: 7608122
- N-(3-aminopropyl)-cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo. | Chu, PJ., et al. 1994. Eur J Pharmacol. 256: 155-60. PMID: 8050466
- Effects of inhibitors of spermidine synthase and spermine synthase on polyamine synthesis in rat tissues. | Shirahata, A., et al. 1993. Biochem Pharmacol. 45: 1897-903. PMID: 8494549
- Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. | Chu, PJ., et al. 1995. Jpn J Pharmacol. 69: 311-5. PMID: 8786633
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
trans-4-Methylcyclohexylamine, 5 g | sc-272662 | 5 g | $184.00 |