Date published: 2025-10-20

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trans-4-Fluorocinnamaldehyde (CAS 51791-26-5)

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Alternate Names:
(E)-3-(4-Fluorophenyl)-2-propenal
CAS Number:
51791-26-5
Molecular Weight:
150.15
Molecular Formula:
C9H7FO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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trans-4-Fluorocinnamaldehyde is a valuable synthetic intermediate with multiple applications in the production of dyes and various organic compounds. Its significance extends to laboratory chemistry, where it serves as a versatile reagent. Moreover, it has played a role in synthesizing novel polymers. In addition to its synthetic utility, this compound has demonstrated inhibitory properties against several enzymes, such as cytochrome P450, cyclooxygenase, and lipoxygenase. Furthermore, it has been found to effectively inhibit the activity of various proteins, including cyclin-dependent kinases and protein kinases.


trans-4-Fluorocinnamaldehyde (CAS 51791-26-5) References

  1. Tricyclic isoxazolines: identification of R226161 as a potential new antidepressant that combines potent serotonin reuptake inhibition and alpha2-adrenoceptor antagonism.  |  Andrés, JI., et al. 2007. Bioorg Med Chem. 15: 3649-60. PMID: 17407815
  2. Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.  |  Li, B., et al. 2018. J Med Chem. 61: 224-250. PMID: 29243920
  3. 1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates.  |  Sun, X., et al. 2022. ChemMedChem. 17: e202100611. PMID: 34704363
  4. Optimizing the Structure of 4‐Dialkylamino‐α, α‐diarylprolinol Ethers as Catalysts for the Enantioselective Cyclopropanation of α, β‐Unsaturated Aldehydes in Water  |  Jose I. Martínez, Prof. Efraim Reyes, Dr. Uxue Uria, Prof. Luisa Carrillo, Prof. Jose L. Vicario. 2013. 5: 2240-2247.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-4-Fluorocinnamaldehyde, 500 mg

sc-237197
500 mg
$100.00