trans-4,5-epoxy-2(E)-Decenal CAS: 134454-31-2
MF: C10H16O2
MW: 168.2
An aldehyde that reacts with nucleophiles on proteins resulting in loss of cell function.

trans-4,5-epoxy-2(E)-Decenal (CAS 134454-31-2)

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Alternate Names: 3-(3-pentyloxiranyl)-2E-propenal; 3- [(2R, 3R)- 3- pentyloxiranyl]- 2E- propenal
Application: trans-4,5-epoxy-2(E)-Decenal is an aldehyde that reacts with nucleophiles on proteins resulting in loss of cell function
CAS Number: 134454-31-2
Purity: >95%
Molecular Weight: 168.2
Molecular Formula: C10H16O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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trans-4,5-epoxy-2(E)-Decenal is an aldehyde compound responsible for the pungent metallic flavor of decomposed lipids. trans-4,5-epoxy-2(E)-Decenal has been shown to react with nucleophiles on proteins, resulting in a loss of cell function and viability. Useful tool in demonstrating the effects (acute and gradual) of peroxidative damage in experimental models.


References

Lin, J., Fay, L.B., Welti, D.H., et al. Quantification of key odorants formed by autoxidation of arachidonic acid using isotope dilution assay. Lipids 36(7) 749-756 (2001). Zamora, R., Hidalgo, F.J. Modification of lysine amino groups by the lipid peroxidation product 4,5(E)-epoxy-2(E)-heptenal. Lipids 29 243-249 (1994).

Formulation :
A solution in methyl acetate
Physical State :
Liquid
Solubility :
Soluble in water (0.2 mg/ml at 25° C), PBS (7.2) (~0.2 mg/ml), ethanol (~30 mg/ml), DMSO (~30 mg/ml), and DMF (~30 mg/ml).
Storage :
Store at -20° C
Boiling Point :
57° C
Refractive Index :
n20D 1.52 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CCCCCC1C(O1)/C=C/C=O

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Certificate of Analysis

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