Date published: 2026-4-30

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trans-2-Methyl-2-butenoyl chloride (CAS 35660-94-7)

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Alternate Names:
Tigloyl chloride; 3-cis-Methyl-methacryloyl chloride; (E)-2-Methylcrotonoyl chloride
CAS Number:
35660-94-7
Molecular Weight:
118.56
Molecular Formula:
C5H7ClO
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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trans-2-Methyl-2-butenoyl chloride possesses the chemical formula C5H7ClO and falls within the category of organochloride compounds. This colorless liquid showcases a potent scent and serves a pivotal role in the creation of diverse organic compounds. Its application extends to catalyzing organic compound synthesis, serving as a reagent for heterocyclic compound formation, and functioning as a fundamental constituent in peptide and protein synthesis, along with the production of fluorescent dyes and other substances.


trans-2-Methyl-2-butenoyl chloride (CAS 35660-94-7) References

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  2. Concise synthesis of anti-HIV-1 active (+)-inophyllum B and (+)-calanolide A by application of (-)-quinine-catalyzed intramolecular oxo-Michael addition.  |  Sekino, E., et al. 2004. J Org Chem. 69: 2760-7. PMID: 15074925
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  5. Gibepyrone Biosynthesis in the Rice Pathogen Fusarium fujikuroi Is Facilitated by a Small Polyketide Synthase Gene Cluster.  |  Janevska, S., et al. 2016. J Biol Chem. 291: 27403-27420. PMID: 27856636
  6. Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson's Disease.  |  Ham, S., et al. 2019. Int J Mol Sci. 20: PMID: 31689937
  7. Metabolomics-guided discovery of cytochrome P450s involved in pseudotropine-dependent biosynthesis of modified tropane alkaloids.  |  Sadre, R., et al. 2022. Nat Commun. 13: 3832. PMID: 35780230
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-2-Methyl-2-butenoyl chloride, 1 g

sc-237165
1 g
$97.00