Molecular structure of Tranexamic acid, CAS Number: 1197-18-8
Tranexamic acid (CAS 1197-18-8)
See product citations (10)
Alternate Names:
Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-; trans-4-(Aminomethyl)cyclohexanecarboxylic acid; AMCA
Application:
Tranexamic acid is an antifibrinolytic agent that inhibits plasmin-induced fibrinolysis by binding plasmin
CAS Number:
1197-18-8
Purity:
>99%
Molecular Weight:
157.21
Molecular Formula:
C8H15NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tranexamic acid is a derivative of the amino acid lysine. Tranexamic acid functions as an antifibrinolytic agent by inhibiting the activation of plasminogen to plasmin, which in turn prevents the degradation of fibrin clots. This makes it effective in reducing bleeding by stabilizing blood clots and preventing their breakdown.
Tranexamic acid (CAS 1197-18-8) References
- Tranexamic acid: a review of its use in surgery and other indications. | Dunn, CJ. and Goa, KL. 1999. Drugs. 57: 1005-32. PMID: 10400410
- Tranexamic acid: a review of its use in the treatment of hyperfibrinolysis. | McCormack, PL. 2012. Drugs. 72: 585-617. PMID: 22397329
- The current place of tranexamic acid in the management of bleeding. | Hunt, BJ. 2015. Anaesthesia. 70 Suppl 1: 50-3, e18. PMID: 25440395
- Tranexamic acid: a clinical review. | Ng, W., et al. 2015. Anaesthesiol Intensive Ther. 47: 339-50. PMID: 25797505
- Tranexamic acid-associated seizures: Causes and treatment. | Lecker, I., et al. 2016. Ann Neurol. 79: 18-26. PMID: 26580862
- Tranexamic Acid Update in Trauma. | Ramirez, RJ., et al. 2017. Crit Care Clin. 33: 85-99. PMID: 27894501
- Topical Tranexamic Acid Is Effective in Cementless Total Knee Arthroplasty. | Chambers, S., et al. 2020. Orthop Clin North Am. 51: 7-11. PMID: 31739881
- Tranexamic acid: current use in obstetrics, major orthopedic, and trauma surgery. | Wong, J., et al. 2021. Can J Anaesth. 68: 894-917. PMID: 33993459
- Tranexamic acid for prevention of bleeding in cesarean delivery: An overview of systematic reviews. | Hurskainen, T., et al. 2022. Acta Anaesthesiol Scand. 66: 3-16. PMID: 34514595
- Clinical use of tranexamic acid: evidences and controversies. | Colomina, MJ., et al. 2022. Braz J Anesthesiol. 72: 795-812. PMID: 34626756
- Tranexamic acid - A narrative review for the emergency medicine clinician. | Wang, K. and Santiago, R. 2022. Am J Emerg Med. 56: 33-44. PMID: 35364476
- Tranexamic acid: Beyond antifibrinolysis. | Prudovsky, I., et al. 2022. Transfusion. 62 Suppl 1: S301-S312. PMID: 35834488
- Tranexamic acid for safer surgery: the time is now. | , ., et al. 2022. Br J Anaesth. 129: 459-461. PMID: 36070986
Inhibitor of:
α-1-Microglobulin, C1r, C1rL, C1s, Corin, Factor XIII A, granzyme M, HABP2, Kininogen I, Kininogen II, KLK (Kallikrein related peptidase), Mast Cell Protease, Mast Cell Protease 8, neuroserpin, OTTMUSG00000019145, P protein, PAI-2, period, plasma kallikrein, PN-1, Prothrombin, Prss34, SerpinA2, SERPINE3, SERPINF2, SPINK3, tetranectin, TFPI-2, TPSB1, TPSB3, Tryptase γ, and uPA.Activator of:
C1INH, Chromozym t-PA, Elastase-3, Enterokinase LC, Factor VIII, Klk26, KLK5, Klkb16, Klkb21, KLKb8, plasma kallikrein, PLGLB1, Prss39, SerpinA1a, SerpinA1c, SERPINE3, and stefin A3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tranexamic acid, 5 g | sc-204921 | 5 g | $29.00 | |||
Tranexamic acid, 10 g | sc-204921A | 10 g | $50.00 |