Toxopyrimidine (CAS 73-67-6)
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Toxopyrimidine is a chemical that is particularly relevant in the study of nucleic acid analogs and their interactions within cellular systems. It is utilized in the field of molecular biology to investigate the inhibition of nucleic acid synthesis, which provides insights into the fundamental mechanisms of gene expression and replication. As a structural analog of naturally occurring pyrimidines, toxopyrimidine is employed to understand the structural requirements for the incorporation of these bases into DNA or RNA. This research helps to understand enzyme-substrate recognition and could contribute to the development of novel research tools for genetic engineering. Moreover, toxopyrimidine′s behavior in chemical assays serves as a point of comparison for the development of new synthetic pyrimidine derivatives.
Toxopyrimidine (CAS 73-67-6) References
- A correlation between changes in gamma-aminobutyric acid metabolism and seizures induced by antivitamin B6. | Abe, M. and Matsuda, M. 1976. J Biochem. 80: 1165-71. PMID: 1002683
- Studies on antivitamin B6 activity of toxopyrimidine. | SHINTANI, S. 1956. J Vitaminol (Kyoto). 2: 185-92. PMID: 13385951
- Antagonistic action of pyridoxine to toxopyrimidine on the growth of mice. | KINOSHITA, T. and TORIGOE, KI. 1956. J Vitaminol (Kyoto). 2: 239-41. PMID: 13385959
- The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine. | RINDI, G. and FERRARI, G. 1959. Nature. 183: 608-9. PMID: 13632808
- Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain. | RINDI, G., et al. 1959. Nature. 183: 1126-7. PMID: 13657025
- Effects of pyridoxine, gamma-aminobutyric acid and gamma-amino-beta-hydroxybutyric acid on the convulsions of dogs caused by toxopyrimidine or isonicotinic acid hydrazide. | KOGUCHI, H. 1962. J Vitaminol (Kyoto). 8: 1-9. PMID: 14457795
- [A study on rabbit's behaviour change before convulsion by toxopyrimidine and its relation to EEG change of the hippocampus]. | Nagano, T. 1966. Sapporo Igaku Zasshi. 30: 27-48. PMID: 6010347
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Toxopyrimidine, 250 mg | sc-397337 | 250 mg | $364.00 |