Molecular structure of Tomatine, CAS Number: 17406-45-0
Tomatine (CAS 17406-45-0)
See product citations (8)
Alternate Names:
Lycopersicin
Application:
Tomatine is an antiproliferatve agent of breast adenocarcinoma cells
CAS Number:
17406-45-0
Purity:
>75%
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Tomatine is an antiproliferatve agent of breast adenocarcinoma cells. Tomatine is a glycoalkaloid compound naturally occurring in tomatoes (Solanum lycopersicum). Its potential health benefits have been extensively studied, revealing properties like antioxidative and anti-inflammatory effects. It inhibit the growth of specific cancer cells and act as an antioxidant, countering free radical damage.
Tomatine (CAS 17406-45-0) References
- The ultrastructure of tomatine adjuvant. | Yang, YW., et al. 2002. Biomaterials. 23: 4677-86. PMID: 12322989
- Immunobiology of the Tomatine adjuvant. | Morrow, WJ., et al. 2004. Vaccine. 22: 2380-4. PMID: 15193398
- Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)-induced liver and stomach tumors in rainbow trout. | Friedman, M., et al. 2007. Mol Nutr Food Res. 51: 1485-91. PMID: 17979099
- Tomatine adjuvantation of protective immunity to a major pre-erythrocytic vaccine candidate of malaria is mediated via CD8+ T cell release of IFN-gamma. | Heal, KG. and Taylor-Robinson, AW. 2010. J Biomed Biotechnol. 2010: 834326. PMID: 20300588
- Differential effect of tomatine and its alleviation by cholesterol on larval growth and efficiency of food utilization inHeliothis zea andSpodoptera exigua. | Bloem, KA., et al. 1989. J Chem Ecol. 15: 387-98. PMID: 24271452
- Protective effect of tomatine against hydrogen peroxide-induced neurotoxicity in neuroblastoma (SH-SY5Y) cells. | Huang, SL., et al. 2014. J Pharm Pharmacol. 66: 844-54. PMID: 24392651
- The role of tomatine adjuvant in antigen delivery for cross- presentation. | Hsu, PY., et al. 2015. Curr Drug Deliv. 12: 342-50. PMID: 26054535
- Tomatine Content in Host and Transgenic Tomatoes by Absorptiometric Measurement. | Furui, H., et al. 1998. Biosci Biotechnol Biochem. 62: 556-7. PMID: 27315931
- The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model. | Yelken, BÖ., et al. 2017. Gene. 627: 408-411. PMID: 28669925
- The Effect of Tomatine on Gene Expression and Cell Monolayer Integrity in Caco-2. | Arena, MP., et al. 2018. Molecules. 23: PMID: 29533987
- RNA-Seq Analyses of Midgut and Fat Body Tissues Reveal the Molecular Mechanism Underlying Spodoptera litura Resistance to Tomatine. | Li, Q., et al. 2019. Front Physiol. 10: 8. PMID: 30723417
- Tomato roots secrete tomatine to modulate the bacterial assemblage of the rhizosphere. | Nakayasu, M., et al. 2021. Plant Physiol. 186: 270-284. PMID: 33619554
- In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma. | Echeverría, C., et al. 2022. Front Pharmacol. 13: 1003264. PMID: 36160442
- Isomers of the Tomato Glycoalkaloids α-Tomatine and Dehydrotomatine: Relationship to Health Benefits. | Kozukue, N., et al. 2023. Molecules. 28: PMID: 37110854
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tomatine, 25 mg | sc-296548A | 25 mg | $130.00 | |||
Tomatine, 50 mg | sc-296548B | 50 mg | $223.00 | |||
Tomatine, 100 mg | sc-296548 | 100 mg | $359.00 | |||
Tomatine, 250 mg | sc-296548C | 250 mg | $785.00 | |||
Tomatine, 500 mg | sc-296548D | 500 mg | $1358.00 |