Date published: 2026-3-7

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Tolylfluanid (CAS 731-27-1)

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CAS Number:
731-27-1
Molecular Weight:
347.26
Molecular Formula:
C10H13Cl2FN2O2S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tolylfluanid is a chemical that functions as a fungicide, inhibiting the growth of fungi and preventing the spread of fungal in plants. It acts by disrupting the function of enzymes involved in the biosynthesis of fungal cell walls, leading to the inhibition of fungal growth and reproduction. It targets the chitin synthase enzyme, which is for the formation of fungal cell walls, leading to the weakening and eventual death of the fungal cells. This mechanism of action disrupts the structural integrity of the fungal cell wall, ultimately leading to the collapse of the fungal cells and preventing the spread of fungal in plants. In the experimental, Tolylfluanid′s mechanism of action at the molecular level provides insights into its potential for studying fungal cell wall biosynthesis and developing strategies for controlling fungal in agricultural.


Tolylfluanid (CAS 731-27-1) References

  1. Investigation on fungicide residues in greenhouse-grown strawberries.  |  Stensvand, A. and Christiansen, A. 2000. J Agric Food Chem. 48: 917-20. PMID: 10725174
  2. Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries.  |  Christensen, HB., et al. 2003. Food Addit Contam. 20: 728-41. PMID: 13129790
  3. In vitro effect of pesticides (dichlofluanid, endosulfan, simazine, tolylfluanid and triallate) on proliferative activity of animal derived cell cultures.  |  Holovská, V., et al. 2007. Acta Biol Hung. 58: 61-74. PMID: 17385544
  4. Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris.  |  McQuilken, MP. and Thomson, J. 2008. Pest Manag Sci. 64: 748-54. PMID: 18286666
  5. Probabilistic acute dietary exposure assessments to captan and tolylfluanid using several European food consumption and pesticide concentration databases.  |  Boon, PE., et al. 2009. Food Chem Toxicol. 47: 2890-8. PMID: 19709586
  6. Effects of seven antifouling compounds on photosynthesis and inorganic carbon use in sugar kelp Saccharina latissima (Linnaeus).  |  Johansson, P., et al. 2012. Arch Environ Contam Toxicol. 63: 365-77. PMID: 22743627
  7. Dietary exposure to the endocrine disruptor tolylfluanid promotes global metabolic dysfunction in male mice.  |  Regnier, SM., et al. 2015. Endocrinology. 156: 896-910. PMID: 25535829
  8. Increase in intracellular Ca(2+) level by phenylsulfamide fungicides, tolylfluanid and dichlofluanid, in rat thymic lymphocytes.  |  Fukunaga, E., et al. 2015. Environ Toxicol Pharmacol. 40: 149-55. PMID: 26119233
  9. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid.  |  Chen, Y., et al. 2018. Endocrinology. 159: 609-621. PMID: 29126303
  10. Cellular fatty acid level regulates the effect of tolylfluanid on mitochondrial dysfunction and insulin sensitivity in C2C12 skeletal myotubes.  |  Davis, AF., et al. 2018. Biochem Biophys Res Commun. 505: 392-398. PMID: 30262144
  11. A simple GC-MS method for the determination of diphenylamine, tolylfluanid propargite and phosalone in liver fractions.  |  Kadar, A., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1113: 69-76. PMID: 30901731
  12. Developmental exposure to the endocrine disruptor tolylfluanid induces sex-specific later-life metabolic dysfunction.  |  Ruiz, D., et al. 2019. Reprod Toxicol. 89: 74-82. PMID: 31260803
  13. Tolylfluanid permeates human skin slowly and as dimethylamino sulfotoluidid (DMST).  |  Berthet, A., et al. 2020. Toxicol Lett. 324: 38-45. PMID: 32062017
  14. Abiotic fate of tolylfluanid and dichlofluanid in natural waters.  |  Cai, Y., et al. 2021. Sci Total Environ. 752: 142160. PMID: 33207498
  15. Biodegradation of third-generation organic antifouling biocides and their hydrolysis products in marine model systems.  |  Koning, JT., et al. 2021. J Hazard Mater. 406: 124755. PMID: 33316671

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tolylfluanid, 250 mg

sc-253711
250 mg
$112.00