Molecular structure of Toltrazuril, CAS Number: 69004-03-1
Toltrazuril (CAS 69004-03-1)
See product citations (1)
Alternate Names:
1-methyl-3-{3-methyl-4-(4-(trifluoromethylthio)phenoxy)phenyl}-1,3,5-triazine-2,4,6(1h,3h,5h)-trione; Tomoxetine Hydrochloride; Baycox; Bay Vi 9142
Application:
Toltrazuril is an anticoccidial agent that reduces redox enzymes
CAS Number:
69004-03-1
Purity:
≥99%
Molecular Weight:
425.38
Molecular Formula:
C18H14F3N3O4S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Toltrazuril is an antiprotozoal compound used in veterinary research. It is extensively studied for its action against coccidian parasites, which are a significant cause of disease in livestock and poultry. In research, the mechanisms by which Toltrazuril disrupts the life cycle of these parasites are of particular interest; it is known to interfere with the division of the protozoan′s nucleus and mitochondria. Studies also focus on the chemical′s impact on different developmental stages of the parasite, aiming to understand its schizonticidal, coccidiocidal, and sporontocidal activities. Toltrazuril is used in investigations that seek to improve animal health and productivity by controlling protozoal infections, which can lead to better management practices in agricultural settings.
Toltrazuril (CAS 69004-03-1) References
- Toltrazuril treatment to control diaplacental Neospora caninum transmission in experimentally infected pregnant mice. | Gottstein, B., et al. 2005. Parasitology. 130: 41-8. PMID: 15700756
- Toltrazuril treatment of congenitally acquired Neospora caninum infection in newborn mice. | Strohbusch, M., et al. 2009. Parasitol Res. 104: 1335-43. PMID: 19205743
- Relevance and treatment of coccidiosis in domestic pigeons (Columba livia forma domestica) with particular emphasis on toltrazuril. | Krautwald-Junghanns, ME., et al. 2009. J Avian Med Surg. 23: 1-5. PMID: 19530399
- Detection, quantifications and pharmacokinetics of toltrazuril sulfone (Ponazuril) in cattle. | Dirikolu, L., et al. 2009. J Vet Pharmacol Ther. 32: 280-8. PMID: 19646093
- Toltrazuril sulfone sodium salt: synthesis, analytical detection, and pharmacokinetics in the horse. | Dirikolu, L., et al. 2012. J Vet Pharmacol Ther. 35: 265-74. PMID: 21679197
- Toltrazuril does not show an effect against pigeon protozoal encephalitis. | Maier, K., et al. 2015. Parasitol Res. 114: 1603-6. PMID: 25648444
- Experimentally confirmed toltrazuril resistance in a field isolate of Cystoisospora suis. | Shrestha, A., et al. 2017. Parasit Vectors. 10: 317. PMID: 28662668
- Pharmacokinetics of toltrazuril and its metabolites in pregnant and nonpregnant ewes and determination of their concentrations in milk, allantoic fluid, and newborn plasma. | Al-Qadri, RF., et al. 2020. J Vet Pharmacol Ther. 43: 339-346. PMID: 32067240
- Risk of residues of toltrazuril sulfone in eggs after oral administration - Could setting maximum residue limit be helpful? | Pietruk, K., et al. 2021. Food Chem. 360: 130054. PMID: 34020367
- Toltrazuril-Loaded Polymeric Nanocapsules as a Promising Approach for the Preventive Control of Coccidiosis in Poultry. | Baron, LF., et al. 2022. Pharmaceutics. 14: PMID: 35214122
- Migration and toxicity of toltrazuril and its main metabolites in the environment. | Huo, M., et al. 2022. Chemosphere. 302: 134888. PMID: 35561774
- Long-term efficacy of toltrazuril in naïve calves prophylactically treated and experimentally infected with Eimeria spp. | Zapa, DMB., et al. 2022. Parasitol Res. 121: 2571-2578. PMID: 35895113
- Toltrazuril and diclazuril: comparative evaluation of anti-coccidial drugs using a murine model. | Ahmadi, P., et al. 2022. J Vet Med Sci. 84: 1345-1351. PMID: 35922919
Activator of:
TBKBP1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Toltrazuril, 1 g | sc-205867 | 1 g | $66.00 | |||
Toltrazuril, 5 g | sc-205867A | 5 g | $273.00 |