Date published: 2026-4-5

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Tolcide 2230 (CAS 21564-17-0)

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Alternate Names:
Benthiazole; Superdavloxan; TCMTB
Application:
Tolcide 2230 is an antimicrobial agent used as a substitute for chlorophenols
CAS Number:
21564-17-0
Molecular Weight:
238.35
Molecular Formula:
C9H6N2S3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tolcide 2230 is a versatile antimicrobial agent specifically designed to replace chlorophenols in various industrial applications. Widely utilized in the leather, pulp and paper, and water-treatment industries, this biocide effectively controls microbial growth and provides a reliable alternative to traditional chlorophenols. It is a dark brown oil.


Tolcide 2230 (CAS 21564-17-0) References

  1. Benzothiazole, benzotriazole, and their derivates in clothing textiles--a potential source of environmental pollutants and human exposure.  |  Avagyan, R., et al. 2015. Environ Sci Pollut Res Int. 22: 5842-9. PMID: 25342452
  2. Structure-activity relationships of benzothiazole GPR35 antagonists.  |  Abdalhameed, MM., et al. 2017. Bioorg Med Chem Lett. 27: 612-615. PMID: 27989666
  3. Three-Component Reaction of Benzothiazole, Acetylenic Esters, Phenoles; Synthesis of Dialkyl 2-benzo[d]thiazol Derivatives Under Grinding.  |  Fatemi, F., et al. 2017. Comb Chem High Throughput Screen. 20: 338-345. PMID: 28464761
  4. Occurrence of benzothiazole and its derivates in tire wear, road dust, and roadside soil.  |  Zhang, J., et al. 2018. Chemosphere. 201: 310-317. PMID: 29525659
  5. Benzothiazole analogs as potential anti-TB agents: computational input and molecular dynamics.  |  Venugopala, KN., et al. 2019. J Biomol Struct Dyn. 37: 1830-1842. PMID: 29697293
  6. Chemicals from textiles to skin: an in vitro permeation study of benzothiazole.  |  Iadaresta, F., et al. 2018. Environ Sci Pollut Res Int. 25: 24629-24638. PMID: 29911295
  7. Benzothiazole carbamates and amides as antiproliferative species.  |  Videnović, M., et al. 2018. Eur J Med Chem. 157: 1096-1114. PMID: 30179747
  8. RIFM fragrance ingredient safety assessment, benzothiazole, CAS Registry Number 95-16-9.  |  Api, AM., et al. 2018. Food Chem Toxicol. 122 Suppl 1: S355-S361. PMID: 30240730
  9. Synthesis of benzothiazole derivatives as a potent α-glucosidase inhibitor.  |  Gollapalli, M., et al. 2019. Bioorg Chem. 85: 33-48. PMID: 30599411
  10. Benzothiazole inhibits the growth of Phytophthora capsici through inducing apoptosis and suppressing stress responses and metabolic detoxification.  |  Mei, X., et al. 2019. Pestic Biochem Physiol. 154: 7-16. PMID: 30765059
  11. Amoebicidal activity of benzothiazole on Acanthamoeba castellanii cysts and trophozoites and its cytotoxic potentials.  |  Ozpinar, N., et al. 2020. Acta Trop. 203: 105322. PMID: 31887263
  12. Determination of benzotriazole and benzothiazole derivatives in marketed fish by double-vortex-ultrasonic assisted matrix solid-phase dispersion and ultrahigh-performance liquid chromatography-high resolution mass spectrometry.  |  Chen, CH., et al. 2020. Food Chem. 333: 127516. PMID: 32683261
  13. Enantiomeric profiling of a chiral benzothiazole necroptosis inhibitor.  |  Zhu, J., et al. 2021. Bioorg Med Chem Lett. 43: 128084. PMID: 33964444
  14. Unraveling the Compositional and Molecular Features Involved in Lysozyme-Benzothiazole Derivative Interactions.  |  Rial, R., et al. 2021. Molecules. 26: PMID: 34641399
  15. Benzothiazole-Derived Sulfones and Sulfoxides as Reactive Templates for Biothiols and Sulfane Sulfurs.  |  Xu, S., et al. 2022. Org Lett. 24: 2546-2550. PMID: 35352985

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tolcide 2230, 100 mg

sc-396107
100 mg
$270.00

Tolcide 2230, 250 mg

sc-396107A
250 mg
$416.00

Tolcide 2230, 1 g

sc-396107B
1 g
$784.00