Date published: 2025-10-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

Tobramycin (CAS 32986-56-4)

4.0(1)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
Deoxykanamycin B; Distobram; Gernebcin
Application:
Tobramycin is an aminoglycoside antibiotic
CAS Number:
32986-56-4
Purity:
≥98%
Molecular Weight:
467.5
Molecular Formula:
C18H37N5O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Tobramycin is an aminoglycoside compound that is widely used in biological research, particularly focusing on its interaction with bacterial ribosomes. Studies involving tobramycin explore its mechanism of binding to the 16S rRNA of the 30S subunit, inhibiting protein synthesis in prokaryotic cells. This action is of interest in molecular biology for probing ribosome structure and function. Additionally, tobramycin is used in microbiology research to study the development of resistance mechanisms in bacteria, which contributes to a broader understanding of antibiotic resistance. Research on the environmental impact of antibiotics also includes tobramycin, examining its presence and degradation in wastewater treatments to assess the potential for antibiotic dissemination into ecosystems.


Tobramycin (CAS 32986-56-4) References

  1. Elution characteristics of tobramycin from polycaprolactone in a rabbit model.  |  Hendricks, KJ., et al. 2001. Clin Orthop Relat Res. 418-26. PMID: 11716417
  2. Pharmacokinetic studies on tobramycin in horses.  |  Hubenov, H., et al. 2007. J Vet Pharmacol Ther. 30: 353-7. PMID: 17610409
  3. Tobramycin for inhalation in cystic fibrosis: Beyond respiratory improvements.  |  Chuchalin, A., et al. 2009. Pulm Pharmacol Ther. 22: 526-32. PMID: 19616111
  4. Pharmacokinetics of intravitreally injected liposome-encapsulated tobramycin in normal rabbits.  |  Kim, EK. and Kim, HB. 1990. Yonsei Med J. 31: 308-14. PMID: 2077755
  5. Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin.  |  Ruddy, J., et al. 2013. J Aerosol Med Pulm Drug Deliv. 26: 69-75. PMID: 22620494
  6. Pharmacokinetics of tobramycin following intravenous, intramuscular, and intra-articular administration in healthy horses.  |  Newman, JC., et al. 2013. J Vet Pharmacol Ther. 36: 532-41. PMID: 23531033
  7. Targeted release of tobramycin from a pH-responsive grafted bilayer challenged with S. aureus.  |  Lee, HS., et al. 2015. Biomacromolecules. 16: 650-9. PMID: 25585173
  8. Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model.  |  Dhanani, JA., et al. 2019. Anesthesiology. 131: 344-355. PMID: 31107274
  9. Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-Negative Bacteria.  |  Idowu, T., et al. 2019. J Med Chem. 62: 9103-9115. PMID: 31557020
  10. Incorporating Fullerenes in Nanoscale Metal-Organic Matrixes: An Ultrasensitive Platform for Impedimetric Aptasensing of Tobramycin.  |  Zhang, HW., et al. 2022. ACS Appl Mater Interfaces. 14: 7350-7357. PMID: 35076206
  11. Thymus vulgaris essential oil + tobramycin within nanostructured archaeolipid carriers: A new approach against Pseudomonas aeruginosa biofilms.  |  Perez, N., et al. 2022. Phytomedicine. 102: 154179. PMID: 35671606
  12. Tobramycin Nanoantibiotics and Their Advantages: A Minireview.  |  Rosalia, M., et al. 2022. Int J Mol Sci. 23: PMID: 36430555
  13. Influence of a bacterial lipopolysaccharide on the pharmacokinetics of tobramycin in rats.  |  Nadai, M., et al. 1993. J Pharm Pharmacol. 45: 971-4. PMID: 7908039

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tobramycin, 10 mg

sc-204917
10 mg
$60.00

Tobramycin, 50 mg

sc-204917A
50 mg
$66.00

Is there an expiry date for tobramycin? How long can it be used in solution if stored at -20°C?

Asked by: seK11
Thank you for your question. Expiry dates are lot-dependent. Please contact our technical service team for specific information.
Answered by: Tech Support Europe
Date published: 2024-03-28
  • y_2025, m_9, d_24, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_204917, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from I will rate this product a 4 and rate 5I will rate this product a 4 and rate 5 for your logistics, customer service and support.
Date published: 2015-04-20
  • y_2025, m_9, d_24, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_204917, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
Tobramycin is rated 4.0 out of 5 by 1.
  • y_2025, m_9, d_24, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_204917, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 117ms
  • REVIEWS, PRODUCT