TNF-R1 Antibody (H398): sc-52739
- TNF-R1 Antibody (H398) is a mouse monoclonal IgG2a, cited in 8 publications, provided at 100 µg/ml
- raised against HL-60 human acute promyelocytic leukemia cell line
- recommended for detection of the extracellular and soluble TNF-R1 receptors of human origin by WB, IP, IF and FCM
- See TNF-R1 (H-5): sc-8436 for TNF-R1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TNF-R1 Antibody (H398). This work is in progress.
TNF-R1 Antibody (H398) is a mouse monoclonal IgG2a antibody that detects tumor necrosis factor receptor 1 (TNF-R1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). TNF-R1 plays a crucial role in mediating the effects of tumor necrosis factor, a key cytokine involved in inflammation and immune responses. TNF-R1 is primarily located on the surface of various cell types, including immune cells, where TNF-R1 initiates signaling pathways that can lead to cell survival, proliferation, or apoptosis, depending on the context. TNF-R1′s ability to transduce apoptotic signals is particularly important, as TNF-R1 helps regulate programmed cell death, which is essential for maintaining tissue homeostasis and immune system function. Dysregulation of TNF-R1 signaling has been implicated in numerous diseases, including autoimmune disorders and cancer, making TNF-R1 a significant target for therapeutic intervention. Anti-TNF-R1 antibody (H398) is an invaluable tool for researchers studying these pathways and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF-R1 Antibody (H398) | sc-52739 | 100 µg/ml | $322.00 |