TNF-α Inhibitor Inhibitor (CAS 1049741-03-8)
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TNF-α Inhibitor is a compound utilized in biological research to study the role of tumor necrosis factor-alpha (TNF-α) in cellular processes and disease states. By blocking the activity of TNF-α, this inhibitor aids in the elucidation of this cytokine′s involvement in inflammation and the innate immune response. Research employing TNF-α Inhibitor is instrumental in understanding the signaling pathways mediated by TNF-α, including those leading to apoptosis, necroptosis, and the activation of NF-κB. This inhibitor is also critical for investigating the molecular basis of diseases characterized by excessive TNF-α activity, such as autoimmune conditions. Additionally, TNF-α Inhibitor is used to explore the cytokine′s role in cellular communication and the regulation of the immune system.
TNF-α Inhibitor Inhibitor (CAS 1049741-03-8) References
- Small-molecule inhibition of TNF-alpha. | He, MM., et al. 2005. Science. 310: 1022-5. PMID: 16284179
- Profiling drug-induced cell death pathways in the zebrafish lateral line. | Coffin, AB., et al. 2013. Apoptosis. 18: 393-408. PMID: 23413197
- Staphylococcus aureus SaeR/S-Regulated Factors Decrease Monocyte-Derived Tumor Necrosis Factor-α to Reduce Neutrophil Bactericidal Activity. | Sward, EW., et al. 2018. J Infect Dis. 217: 943-952. PMID: 29272502
- Inflammation, Autophagy, and Apoptosis After Myocardial Infarction. | Wang, X., et al. 2018. J Am Heart Assoc. 7: PMID: 29680826
- TNF-α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate-induced osteoarthritis. | Li, H., et al. 2018. Exp Ther Med. 16: 4737-4744. PMID: 30542428
- Molecular and Electrophysiological Role of Diabetes-Associated Circulating Inflammatory Factors in Cardiac Arrhythmia Remodeling in a Metabolic-Induced Model of Type 2 Diabetic Rat. | Zayas-Arrabal, J., et al. 2021. Int J Mol Sci. 22: PMID: 34202017
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF-α Inhibitor, 5 mg | sc-356160 | 5 mg | $745.00 |