Molecular structure of TMPO, CAS Number: 10135-38-3
TMPO (CAS 10135-38-3)
Alternate Names:
3,3,5,5-Tetramethyl-1-pyrroline N-Oxide
Application:
TMPO is a solid, cell-permeable and hygroscopic spin trap
CAS Number:
10135-38-3
Purity:
≥95%
Molecular Weight:
141.2
Molecular Formula:
C8H15NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TMPO, or 3,3,5,5-tetramethyl-1-pyrroline-1-oxide, is a pyrroline-based N-oxyl spin trap. TMPO is described for use as a cell-permeable spin trap probe for ESR studies of biological systems.
TMPO (CAS 10135-38-3) References
- Comparison of 2,5,5-trimethyl-1-pyrroline-N-oxide (M3PO) and 3,3,5,5-tetramethyl-1-pyrroline-N-oxide (M4PO) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as spin traps. | Nishi, M., et al. 1992. Biochem Int. 27: 651-9. PMID: 1417898
- The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide). | Buettner, GR. and Britigan, BE. 1990. Free Radic Biol Med. 8: 57-60. PMID: 2157635
- Evaluation of Zeolite Acidity by 31P MAS NMR Spectroscopy of Adsorbed Phosphine Oxides: Quantitative or Not? | Zasukhin, DS., et al. 2022. ACS Omega. 7: 12318-12328. PMID: 35449977
- Silencing DTX3L Inhibits the Progression of Cervical Carcinoma by Regulating PI3K/AKT/mTOR Signaling Pathway. | Hu, W., et al. 2023. Int J Mol Sci. 24: PMID: 36614304
- Epigenetic and Tumor Microenvironment for Prognosis of Patients with Gastric Cancer. | Wu, Z., et al. 2023. Biomolecules. 13: PMID: 37238607
- Identification of genetic variants affecting reproduction traits in Vrindavani cattle. | Gangwar, M., et al. 2024. Mamm Genome. 35: 99-111. PMID: 37924370
- c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer. | Gui, Y., et al. 2024. Cell Death Dis. 15: 61. PMID: 38233377
- The expression and role of the Lem-D proteins Ankle2, Emerin, Lemd2, and TMPO in triple-negative breast cancer cell growth. | Rose, M., et al. 2024. Front Oncol. 14: 1222698. PMID: 38720803
- Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis. | Slater, AF., et al. 1995. Biochem J. 306 (Pt 3): 771-8. PMID: 7702573
- The effect of myoglobin on the stability of the hydroxyl-radical adducts of 5,5 dimethyl-1-pyrolline-N-oxide (DMPO), 3,3,5,5 tetramethyl-1-pyrolline-N-oxide (TMPO) and 1-alpha-phenyl-tert-butyl nitrone (PBN) in the presence of hydrogen peroxide. | De Bono, D., et al. 1994. Free Radic Res. 20: 327-32. PMID: 8069390
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMPO, 100 mg | sc-202365 | 100 mg | $47.00 | |||
TMPO, 250 mg | sc-202365A | 250 mg | $109.00 |