TMIO CAS: 136440-22-7
MF: C6H10N2O
MW: 126.2
A selective, non-toxic, and cell permeable spin trap for peroxynitrite and secondary O-, C-, S-, & N- centered free radicals..

TMIO (CAS 136440-22-7)

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Alternate Names: 2,2,4-Trimethyl-2H-imidazole-1-oxide
Application: TMIO is a selective, non-toxic, and cell permeable spin trap for peroxynitrite and secondary O-, C-, S-, & N- centered free radicals.
CAS Number: 136440-22-7
Purity: ≥98%
Molecular Weight: 126.2
Molecular Formula: C6H10N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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TMIO is a selective, cell permeable and non-toxic spin trap for peroxynitrite and secondary O-, C-, S-, and N- centered free radicals.


References

1. Dikalov, S., et al. 1996. Biochem. Biophys Res. Commun. 218: 616-622. PMID: 8561805
2. Dikalov, S., et al. 1996. Arch. Biochem. Biophys. 326: 207-218. PMID: 8611025
3. Krainev, A.G., et al. 1996. J. Magn. Reson. B. 111: 272-280. PMID: 8661292
4. Dikalov, S., et al. 1997. Biochem. Biophys. Res. Commun. 230: 54-57. PMID: 9020059
. 5. Dikalov, S., et al. 1997. Biochem. Biophys. Res. Commun. 231: 701-704. PMID: 9070876
6. Dikalov, S., et al. 1998. J. Cardiovasc. Pharmacol. Ther. 3: 51-62 . PMID: 10684481
7. Dikalov, S.I., et al. 1999. Free Radic. Biol. Med. 27: 864-872. PMID: 10515591

Physical State :
Solid
Solubility :
Soluble in DMSO, water, methanol, and 100% ethanol.
Storage :
Store at -20° C
Melting Point :
32-36° C (lit.)
Refractive Index :
n20D 1.52 (Predicted)
pK Values :
pKb: 0.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
379378
MDL Number :
MFCD00168351
Beilstein Registry :
5424342
SMILES :
CC1=NC(C)(C)[N+](=C1)[O-]

Download SDS (MSDS)

Certificate of Analysis

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